3 results on '"Bradley-Stewart, Amanda"'
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2. European surveillance for enterovirus D68 during the emerging North-American outbreak in 2014
- Author
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Poelman, Randy, Schuffenecker, Isabelle, Van Leer-Buter, Coretta, Josset, Laurence, Niesters, Hubert G. M., Lina, Bruno, Popow-Kraupp, Theresia, Aberle, Stephan W., Fischer, Thea Kølsen, Midgley, Sofie, Christiansen, Claus Bohn, Waris, Matti, Österback, Riikka, Vuorinen, Tytti, Savolainen-Kopra, Carita, Latronico, Francesca, Blomqvist, Soile, Ikonen, Niina, Lappalainen, Maija, Jääskeläinen, Anne, Smura, Teemu, Pilorge, Léa, Legrand-Quillien, Marie-Christine, Payan, Christopher, Petitjean, Joëlle, Vabret, Astrid, Ribault, Mélanie, Mirand, Audrey, Peigue-Lafeuille, Hélène, Henquell, Cécile, Manoha, Catherine, Bour, Jean-Baptiste, Darniot, Magali, Le Goff, Jérôme, Mercier-Delarue, Séverine, Scieux, Catherine, Pillet, Sylvie, Pozzetto, Bruno, Lepiller, Quentin, Fafi-Kremer, Samira, Stoll-Keller, Françoise, Marque-Juillet, Stéphanie, Coutard, Aymeric, Amara, Marlène, Böttcher, Sindy, Diedrich, Sabine, Eis-Hübinger, Anna Maria, Aldabbagh, Souhaib, Reber, Ulrike, Panning, Marcus, Huzly, Daniela, Bierbaum, Sibylle, Liebert, Uwe G., Maier, Melanie, Carr, Michael J., Tuite, Gráinne, Guerra, Jorge Abboud, O'Gorman, Joanne, De Gascun, Cillian, Baldanti, Fausto, Piralla, Antonio, Esposito, Susanna, Principi, Nicola, Ruggiero, Luca, Opp, Matthias, Donker, Gé, Meijer, Adam, van der Avoort, Harrie, Benschop, Kimberley, de Lange, Marit, Niesters, Hubert, Borger, Renze, Scholvinck, Liesbeth, van der Reijden, Wil, Veenendaal, Dick, Claas, Eric C. J., Vossen, Ann C. T. M., Rahamat-Langendoen, Janette, Melchers, Willem J. G., Koopmans, Marion P. G., van der Eijk, Annemiek A., Pas, Suzan D., Kran, Anne-Marte Bakken, Bragstad, Karoline, Dudman, Susanne Gjeruldsen, Christensen, Andreas, Krokstad, Sidsel, Pancer, Katarzyna, Abramczuk, Edyta, Guiomar, Raquel, Pechirra, Pedro, Cristovão, Paula, Costa, Ines, Tecu, Cristina, Lupulescu, Emilia, Cherciu, Carmen, Goldstein, Emily, Bennett, Susan, Bradley-Stewart, Amanda, Gunson, Rory, Berginc, Natasa, Prosenc, Katarina, Campins, Magda, Gimferrer, Laura, Anton, Andres, López-Labrador, F. Xavier, Pérez, Laura Cano, Puig-Barberá, Joan, Cardona, Concepción Gimeno, Mochón, M Dolores Ocete, Buesa, Javier, Navarro, David, de Lejarazu Leonardo, R. Ortiz, Muñoz, Iván Sanz, Rojo, Silvia, Gozalo-Margüello, Mónica, Balbín, Jesús Agüero, Albert, Jan, Samuelson, Agneta, Östlund, Maria Rotzén, Dyrdak, Robert, Brytting, Mia, Hauzenberger, Elenor, Zakikhany, Katherina, Eriksson, Margareta, Moore, Catherine, Broberg, Eeva, Penttinen, Pasi, Mcculloch, Elaine, Di Lorenzo, Caterina, Wallace, Paul, Van Loon, Anton, Prifert, Christiane, Weißbrich, Benedikt, Adams, Ortwin, Berlin, Labor, Hofmann, Jörg, Schnitzler, Paus, Microbes in Health and Disease (MHD), Laboratoire de Biologie et de Pharmacologie Appliquée (LBPA), École normale supérieure - Cachan (ENS Cachan)-Centre National de la Recherche Scientifique (CNRS), Virologie et pathologie humaine (VirPath), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon, Laboratoire Microorganismes : Génome et Environnement (LMGE), Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020]), Virology, Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre National de la Recherche Scientifique (CNRS), Department of Virology, Medicum, and Viral Zoonosis Research Unit
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Male ,Pediatrics ,NETHERLANDS ,CHILDREN ,medicine.disease_cause ,Disease Outbreaks ,EMERGENCE ,Respiratory infection ,Epidemiology ,Prospective Studies ,Child ,ComputingMilieux_MISCELLANEOUS ,Aged, 80 and over ,Enterovirus D, Human ,318 Medical biotechnology ,Women's cancers Radboud Institute for Molecular Life Sciences [Radboudumc 17] ,Middle Aged ,3. Good health ,Europe ,Geography ,Infectious Diseases ,INFECTIONS ,Child, Preschool ,Molecular epidemiology ,Epidemiological Monitoring ,[SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology ,Female ,Enterovirus D68 ,VP1 sequencing ,Adult ,medicine.medical_specialty ,Adolescent ,INHIBITION ,Enterovirus D ,ta3111 ,[SDV.MP.PRO]Life Sciences [q-bio]/Microbiology and Parasitology/Protistology ,RESPIRATORY ILLNESS ,Young Adult ,SDG 3 - Good Health and Well-being ,Virology ,Enterovirus Infections ,medicine ,Humans ,Disease burden ,Aged ,Retrospective Studies ,Viral Structural Proteins ,PEDIATRIC-PATIENTS ,business.industry ,Infant, Newborn ,ta1182 ,Infant ,Outbreak ,Retrospective cohort study ,Sequence Analysis, DNA ,[SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology ,Molecular Typing ,lnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4] ,VIRAL 2A PROTEASE ,HUMAN RHINOVIRUS ,North America ,REPLICATION ,Enterovirus ,business - Abstract
M. Lappalainen, A. Jääskeläinen ja T. Smura ovat työryhmän ESCV-ECDC EV-D68 Study Grp jäseniä. Background: In August and September 2014, unexpected clusters of enterovirus-D68 (EV-D68) infections associated with severe respiratory disease emerged from North-America. In September, the European Centre for Disease Prevention and Control (ECDC) asked European countries to strengthen respiratory sample screening for enterovirus detection and typing in cases with severe respiratory presentations. Objectives: To provide a detailed picture of EV-D68 epidemiology in Europe by conducting a retrospective and prospective laboratory analysis of clinical specimens. Study design: An initiative supported by the European Society for Clinical Virology (ESCV) and ECDC was launched to screen for EV-D68 in respiratory specimens between July 1st and December 1st 2014 in Europe and to sequence the VP1 region of detected viruses for phylogenetic analytic purposes. Results: Forty-two institutes, representing 51 laboratories from 17 European countries, analyzed 17,248 specimens yielding 389 EV-D68 positive samples (2.26%) in 14 countries. The proportion of positive samples ranged between 0 and 25% per country. These infections resulted primarily in mild respiratory disease, mainly detected in young children presenting with wheezing and in immuno-compromised adults. The viruses detected in Europe are genetically very similar to those of the North-American epidemic and the majority (83%) could be assigned to clade B. Except for 3 acute flaccid paralysis (AFP) cases, one death and limited ICU admissions, no severe cases were reported. Conclusions: The European study showed that EV-D68 circulated in Europe during summer and fall of 2014 with a moderate disease burden and different pathogenic profile compared to the North-American epidemic. (C) 2015 The Authors. Published by Elsevier B.V.
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- 2015
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3. Hepatitis A—2017 an unusual year in Scotland.
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Bradley-Stewart, Amanda, Smith-Palmer, Alison, Hawkins, Gill, and Gunson, Rory
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HEPATITIS A , *HEPATITIS , *DISEASE risk factors , *GENOTYPES , *SIMULATED patients - Abstract
• Five-fold increased incidence in hepatitis A in Scotland in 2017. • Majority (99%) of cases had no obvious risk factors for acquiring hepatitis A. • 44% of cases had strains which were associated with MSM outbreaks in Europe. • 44% of cases were genotype 1B and fell into four separate clusters. • Identified identical cases in geographically distinct regions with no epidemiological links. The number of cases of acute hepatitis A reported in Scotland each year is small, and the majority of cases have been associated with travel to endemic regions. However, in early 2017, in the midst of ongoing outbreaks of hepatitis A among MSM in Europe, there was a sharp rise in the number of cases reported to Health Protection Scotland. The initial aim of this study was to investigate the reason for the observed increase in cases of hepatitis A at the start of 2017. As cases continued for the remainder of the year, these cases were typed to determine whether these cases were linked to each other, or other outbreaks. The study population consisted of 42 hepatitis A infected patients with no obvious source of infection. The patient samples were collected between January and December 2017. The VP1/2 A region was amplified and sequenced. The majority of samples typed as genotype 1 A (n = 17) or genotype 1B (n = 15). Within genotype 1 A, fifteen samples had strains (VRD_521_2016 or RIVM_HAV16_090) associated with ongoing outbreaks of hepatitis A in MSM in Europe. Within genotype 1B, there were four clusters of infections, with identical cases in geographically distinct regions with no identified epidemiological link. Molecular typing proved useful, as it allowed public health to identify clusters, establish links with other outbreaks and compare Scottish strains with those reported elsewhere. [ABSTRACT FROM AUTHOR]
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- 2019
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