1. Clinical Manifestations of Patients with Coronavirus Disease 2019 (COVID-19) in a Referral Center in Iran
- Author
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Baghaei, P., Nadji, S. A., Tabarsi, P., Velayati, A. A., Marjani, M., Moniri, A., Hashemian, S. M., Sheikhzade, H., Abtahian, Z., Heshmatnia, J., Abedini, A., Jamaati, H., Mansourafshar, B., Ahmadi, Z. H., Dezfuli, M. M., Seifi, S., Sadeghi, M., Mirenayat, M. S., Yassari, F., Lookzadeh, S., Farzanegan, B., Kiani, A., Vasheghani, M., Dastan, F., Eslaminejad, A., Malekmohammad, M., Varahram, M., and Alireza Zali
- Subjects
ICU ,COVID-19 ,Original Article ,Outcomes ,Features - Abstract
Background: Following the recent epidemic of coronavirus disease 2019 (COVID-19) in Wuhan, China, a novel betacoronavirus was isolated from two patients in Iran on February 19, 2020. In this study, we aimed to determine the clinical manifestations and outcomes of the first confirmed cases of COVID-19 infection (n=127). Materials and Methods: This prospective study was conducted on all COVID-19-suspected cases, admitted to Masih Daneshvari Hospital (a designated hospital for COVID-19), Tehran, Iran, since February 19, 2020. All patients were tested for COVID-19, using reverse transcription-polymerase chain reaction (RT-PCR) assay. Data of confirmed cases, including demographic characteristics, clinical features, and outcomes, were collected and compared between three groups of patients, requiring different types of admission (requiring ICU admission, admission to the general ward, and transfer to ICU). Results: Of 412 suspected cases, with the mean age of 54.1 years (SD=13.4), 127 (31%) were positive for COVID-19. Following the patients’ first visit to the clinic, 115 cases were admitted to the general ward, while ten patients required ICU admission. Due to clinical deterioration in the condition of 25 patients (out of 115 patients), ICU admission was essential. Based on the results, the baseline characteristics of the groups were similar. Patients requiring ICU admission were more likely to have multiorgan involvement (liver involvement, P
- Published
- 2020