1. Live birth using vitrified-warmed oocytes in invasive ovarian cancer: case report and literature review.
- Author
-
Alvarez, Manuel, Solé, Miquel, Devesa, Marta, Fábregas, Rafael, Boada, Montserrat, Tur, Rosa, Coroleu, Buenaventura, Veiga, Anna, and Barri, Pedro N.
- Subjects
- *
CHILDBIRTH , *OVARIAN cancer , *OVUM , *ECTOPIC pregnancy , *FERTILITY preservation , *HETEROTOPIC pregnancy , *FERTILIZATION in vitro , *HUMAN artificial insemination - Abstract
This article reports the live birth of a healthy newborn using vitrified--warmed oocytes in a young patient with invasive mucinous ovarian carcinoma (stage Ic). Diagnosis was performed after a laparoscopic left adnexectomy. She underwent two cycles of ovarian stimulation, and 14 oocytes were vitrified before fertility-sparing surgery with uterus preservation went ahead. One year later, a transfer of two embryos was performed after insemination of warmed oocytes. Eighteen days after the transfer, she underwent a laparotomy because of abdominal pain, vaginal bleeding and haemoperitoneum. A right cornual ectopic pregnancy in the uterus was diagnosed and a wedge resection was performed to resolve it. One week later, a viable intrauterine pregnancy was confirmed under ultrasound. An elective Caesarean section was performed at week 38 of gestation, resulting in the birth of a healthy boy weighing 2650 g. As far as is known, this is the first live birth reported through vitrified-warmed oocytes in a patient with invasive ovarian cancer. Although oocyte vitrification is an alternative to be considered for fertility preservation in highly selected cases of ovarian cancer, controversial issues are discussed. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
- View/download PDF