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Your search keyword '"Brondani, Patrícia B."' showing total 3 results
Start Over Author "Brondani, Patrícia B." Topic oxidation
3 results on '"Brondani, Patrícia B."'

1. Chemoenzymatic approaches to obtain chiral-centered selenium compounds

Author

Brondani, Patrícia B., Guilmoto, Nathalie M.A.F., Dudek, Hanna M., Fraaije, Marco W., and Andrade, Leandro H.

Subjects
*SELENIUM compounds synthesis, *CHIRALITY, *ENANTIOSELECTIVE catalysis, *MONOOXYGENASES, *ASPERGILLUS terreus, *ENZYME kinetics, *OXIDATION
Abstract

Abstract: The synthesis of chiral-centered selenium compounds is presented. Enantioselective oxidations of these organoselenium compounds were performed using a wide range of biocatalysts, including Baeyer–Villiger monooxygenases, oxidoreductases-containing Aspergillus terreus and lipase (Cal-B) in the presence of oxidants. Finally, efficient synthesis of enantiopure organoselenium compounds using a kinetic resolution approach mediated by Cal-B was achieved. [Copyright &y& Elsevier]

Published
2012
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2. Exploiting the enantioselectivity of Baeyer-Villiger monooxygenases via boron oxidation

Author

Brondani, Patrícia B., Dudek, Hanna, Reis, Joel S., Fraaije, Marco W., and Andrade, Leandro H.

Subjects
*MONOOXYGENASES, *BORON compounds, *OXIDATION, *CHEMICAL bonds, *CHIRALITY, *ETHANOL, *ESTERS, *CARBOXYLIC acids
Abstract

Abstract: The enantioselective carbon–boron bond oxidation of several chiral boron-containing compounds by Baeyer-Villiger monooxygenases was evaluated. PAMO and M446G PAMO conveniently oxidized 1-phenylethyl boronate into the corresponding 1-(phenyl)ethanol (ee=82–91%). Cyclopropyl boronic esters were also oxidized but with no enantioselectivity. β-Boryl carboxylic esters were not oxidized by any BVMOs. [Copyright &y& Elsevier]

Published
2012
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3. Oxidation of organoselenium compounds. A study of chemoselectivity of phenylacetone monooxygenase

Author

Andrade, Leandro H., Pedrozo, Eliane C., Leite, Henrique G., and Brondani, Patrícia B.

Subjects
*OXIDATION, *ORGANOSELENIUM compounds, *MONOOXYGENASES, *PHENYL compounds, *KETONES, *CHEMICAL reactions
Abstract

Abstract: Organoselenium acetophenones oxidation using enzymatic reactions has been developed and chemoselectivity of phenylacetone monooxygenase (PAMO) with selenium-containing ketones has been explored. We discovered that this biocatalyst prefers selenium oxidation, which leads to selenoxide in excellent conversion, over Baeyer–Villiger oxidation. [Copyright &y& Elsevier]

Published
2011
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