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1,2,4-Thiadiazoles were efficiently synthesized in good yields through the oxidative dimerization of carbothioamides by using Oxone as a readily available, inexpensive, and environmentally safe oxidant. A similar reaction of phenylselenoamide led to the corresponding 1,2,4-phenylselenadiazole in high yield. [ABSTRACT FROM AUTHOR]

An efficient, transition metal-free procedure for the cyclopropanation of alkenes using malononitrile and the LiI- tBuOCl combination under mild reaction conditions is described. The reaction mechanism most likely involves tBuOI generated in situ from LiI and tBuOCl. The utility of this new methodology has been demonstrated by the synthesis of a potential HIV-1 RT inhibitor. [ABSTRACT FROM AUTHOR]

The article presents chemical equations related to the article "Synthesis of 1,2,4-Thiadiazoles by Oxidative Dimerization of Carbothioamides by Using Oxone" by A. Yoshimura and others, published in the periodical "European Journal of Organic Chemistry" in 2014.