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Ambient air pollution has been regarded as an important cause of the morbidity and mortality of respiratory diseases. In the current work, a total of 469,490 respiratory emergency room (ER) visits in Lanzhou, China from Jan 1, 2013 to Dec 31, 2016 were collected. A generalized additive model (GAM) was used to investigate the association between O 3 and respiratory ER visits for the different gender and age subgroups. The results showed that: (a) with per inter-quartile range (IQR) (31 µg/m 3 ) increase in O 3 , the greatest relative risk (RR) of respiratory ER visits for the total was 1.014 (95% CI 1.008-1.020) at lag 4 days. Females and 16-to-45-year-olds were relatively more sensitive to O 3 ; (b) the significant lag effects were found in single-day lag models, with the highest RR values for different groups were observed at lag 3-lag 5 days. The multi-day cumulative lag effects were stronger for the total; (c) in the multiple-pollutant models, the effects of O 3 were generally increased when introducing other pollutants (PM 10 , PM 2.5 , SO 2 and NO 2 ) for adjustment. This study demonstrated that short-term exposure to O 3 increased the RR of respiratory ER visits in Lanzhou, China., (© 2021. The Author(s), under exclusive licence to Springer Nature B.V.)

In recent years, O 3 pollution had been worsening in China and became a major challenge for human health. To evaluate the O 3 effects on circulatory and respiratory mortality in Harbin, a high latitude city of northeast China, we applied a time-series study from 2014 to 2016. After collecting data and adjusting for the effects of confounders, we built the generalized additive model to assess the associations between O 3 and mortality at different lag days. The results showed that an interquartile-range (IQR) increase in O 3 concentration corresponded to excess risk (ER) of 2.00% (95%CI: - 0.25-4.30%) for circulatory mortality at lag 0 and 8.02% (95%CI: 4.18-12.01%) for respiratory mortality at lag 2 days in the single-pollutant model. Stratified analysis showed that O 3 had a greater effect on females than on males. The effect of O 3 exposure on circulatory mortality was stronger during the warm period, while the opposite trend was founded for respiratory mortality. The sensitivity analysis showed that the effects of O 3 were relatively independent and the major results were robust., (© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)

This systematic review and meta-analysis was performed to obtain updated evidence regarding the short-term effect of ozone on respiratory mortality in China. We systematically searched the Embase, PubMed, Scopus, Web of Science, China National Knowledge Internet, and Wanfang databases for relevant studies. After screening based on the inclusion criteria, 12 studies with 19 estimates were selected for further meta-analysis. The results revealed that respiratory mortality significantly increased by 0.55% (95% confidence interval: 0.24%-0.85%; Q = 39.47, I 2  = 54.4%, P = 0.002, tau 2  < 10 -5 ) for every 10-μg/m 3 increase in the maximum 8-h average concentration of ozone. Furthermore, differences in combined estimates were observed between various regions and lag structures. The combined effect of single-day lags was generally larger than that of multiday lags; the estimate of mortality for the population in the north was larger than that for the population in the south. The sensitivity analysis demonstrated that the main findings were stable; funnel plots with Egger's and Begg's tests indicated no significant publication bias in our analysis., (Copyright © 2021 Elsevier Ltd. All rights reserved.)

In recent years, O3 pollution had been worsening in China and became a major challenge for human health. To evaluate the O3 effects on circulatory and respiratory mortality in Harbin, a high latitude city of northeast China, we applied a time-series study from 2014 to 2016. After collecting data and adjusting for the effects of confounders, we built the generalized additive model to assess the associations between O3 and mortality at different lag days. The results showed that an interquartile-range (IQR) increase in O3 concentration corresponded to excess risk (ER) of 2.00% (95%CI: − 0.25–4.30%) for circulatory mortality at lag 0 and 8.02% (95%CI: 4.18–12.01%) for respiratory mortality at lag 2 days in the single-pollutant model. Stratified analysis showed that O3 had a greater effect on females than on males. The effect of O3 exposure on circulatory mortality was stronger during the warm period, while the opposite trend was founded for respiratory mortality. The sensitivity analysis showed that the effects of O3 were relatively independent and the major results were robust. [ABSTRACT FROM AUTHOR]