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Reported herein is the use of ligands to tune the regioselectivity and reactivity of palladium-catalyzed [3+2] and [3+3] cycloadditions. Diverse synthesis with vinylethylene carbonates (VECs) as well as free naphthols has been explored to construct four different valuable polycyclic frameworks in a broad substrate scope. [ABSTRACT FROM AUTHOR]

A practical and efficient approach for the synthesis of various sulfonyl-substituted vinyl arenes is reported. In the process, hydrazones provide coupling partners for the Pd-catalyzed cross-coupling with aryl halides and sulfinate salts as nucleophiles, which realizes minimal waste and excellent atom economy. [ABSTRACT FROM AUTHOR]

Functionalized 3,4-dihalogenated furan-2(5 H)-ones can be readily prepared in moderate to good yields by treating 4-hydroxy-4-arylbut-2-ynoate derivatives with ICl, IBr, and I2. Both halogen atoms of the electrophile are incorporated in the product. The resulting halides can further afford polycyclic aromatic compounds using known palladium-catalyzed coupling reactions. [ABSTRACT FROM AUTHOR]

The corresponding products can be further converted via Pd-catalyzed coupling reactions [cf. [ABSTRACT FROM AUTHOR]