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Start Over Author "Robinson CJ" Topic parathyroid hormone
15 results on '"Robinson CJ"'

1. The physiology of parathyroid hormone.

Author

Robinson CJ

Subjects
Bone and Bones metabolism, Calcium metabolism, Calcium urine, Cyclic AMP physiology, Diet, Homeostasis, Humans, Hyperparathyroidism diagnosis, Intestinal Absorption drug effects, Kidney metabolism, Kidney physiology, Parathyroid Hormone pharmacology, Phosphates urine, Parathyroid Hormone physiology
Published
1974
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2. Hormone metabolism and response of adenylate cyclase to parathyroid hormone in kidney.

Author

Moseley JM, Martin TJ, Robinson CJ, Reit BW, and Tregear GW

Subjects
Animals, Cell Membrane metabolism, Chickens, In Vitro Techniques, Kidney drug effects, Kidney ultrastructure, Male, Parathyroid Hormone pharmacology, Rats, Adenylyl Cyclases metabolism, Kidney metabolism, Parathyroid Hormone metabolism
Abstract

1. Incubation of parathyroid hormone with plasma membranes from rat kidney cortex resulted in rapid loss of all hormal activity. 2. Chick kidney membranes showed no ability to inactivate parathyroid hormone even with prolonged incubation. 3. Biologically active, labelled parathyroid hormone was degraded to fragments by rat kidney membranes, but not by chick kidney. 4. Hormone-responsive adenylate cyclase activity in a mixture of rat and chick kidney membranes was additive. 5. Parathyroid hormone bound specifically to chick kidney palsma membranes. 6. It is concluded that hormone in activation during incubation has little relevance to the effectiveness of parathyroid hormone in stimulating adenylate cyclase activity in kidney, and furthermore that failure of chick kidney to metabolize the hormone is not the explanation for the greater sensitivity of this species to the hormone.

Published
1975
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3. Effect of oxidation on biological and immunological activity of porcine parathyroid hormone.

Author

O'Riordan JL, Woodhead JS, Hendy GN, Parsons JA, Robinson CJ, Keutmann HT, Dawson BF, and Potts JT Jr

Subjects
Adenylyl Cyclases, Amino Acids analysis, Animals, Biological Assay, Cysteine, Dose-Response Relationship, Drug, Enzyme Activation, Immune Sera, In Vitro Techniques, Iodine Radioisotopes, Methionine analysis, Oxidation-Reduction, Parathyroid Hormone analysis, Radioimmunoassay, Structure-Activity Relationship, Swine, Parathyroid Hormone immunology
Published
1974
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5. Magnesium and the gut: experimental and clinical observations.

Author

MacIntyre I and Robinson CJ

Subjects
Animals, Calcium metabolism, Gastrointestinal Diseases blood, Magnesium Deficiency, Male, Parathyroid Glands physiology, Parathyroid Hormone pharmacology, Rats, Homeostasis, Intestinal Absorption, Magnesium metabolism, Parathyroid Hormone physiology
Published
1969
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8. Structure-function studies in parathyroid hormone.

Author

O'Riordan JL, Woodhead JS, Robinson CJ, Parsons JA, Keutmann H, Niall H, and Potts JT

Subjects
Amino Acid Sequence, Amino Acids analysis, Animals, Cattle, Chromatography, Gas, Chromatography, Thin Layer, Humans, Peptides analysis, Radioimmunoassay, Swine, Parathyroid Hormone analysis, Structure-Activity Relationship
Published
1971

11. Isolation and chemical properties of porcine parathyroid hormone.

Author

Woodhead JS, O'Riordan JL, Keutmann HT, Stoltz ML, Dawson BF, Niall HD, Robinson CJ, and Potts JT Jr

Subjects
Acetone, Amino Acid Sequence, Amino Acids analysis, Animals, Biological Assay, Carboxypeptidases, Cattle, Chemical Phenomena, Chemical Precipitation, Chemistry, Chromatography, Gel, Chromatography, Ion Exchange, Chromatography, Thin Layer, Electrophoresis, Disc, Ethyl Ethers, Formates, Hydrogen Peroxide, Iodine Isotopes, Molecular Weight, Oxidation-Reduction, Parathyroid Glands analysis, Phenols, Radioimmunoassay, Rats, Silicon Dioxide, Sodium Chloride, Solubility, Spectrophotometry, Swine, Trichloroacetic Acid, Ultraviolet Rays, Parathyroid Hormone analysis, Parathyroid Hormone isolation & purification
Published
1971
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14. A chick bioassay for parathyroid hormone.

Author

Parsons JA, Reit B, and Robinson CJ

Subjects
Age Factors, Animals, Calcitonin pharmacology, Calcium blood, Cyclic AMP pharmacology, Diet, Dose-Response Relationship, Drug, Female, Glucagon pharmacology, Half-Life, Histamine pharmacology, Male, Methods, Rats, Species Specificity, Time Factors, Vasopressins pharmacology, Biological Assay, Chickens, Parathyroid Hormone pharmacology
Published
1973
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15. Role of prolactin in vitamin D metabolism and calcium absorption during lactation in the rat

Author

Mark R. Haussler, Robinson Cj, E. Spanos, Makeen Am, J. W. Pike, C. J. Hillyard, Iain MacIntyre, and James Mf

Subjects
Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Parathyroid hormone, Endocrinology, Calcitriol, Pregnancy, Internal medicine, Lactation, medicine, Animals, Bromocriptine, Calcium metabolism, Vitamin D metabolism, Chemistry, Rats, Inbred Strains, Plasma levels, Alkaline Phosphatase, Prolactin, Rats, medicine.anatomical_structure, Intestinal Absorption, Alkaline phosphatase, Calcium, Female, medicine.drug
Abstract

Intestinal calcium absorption and plasma levels of 1,25-dihydroxycholecalciferol (1,25(OH)2D3) were measured in lactating and non-lactating rats and the effects of bromocriptine and exogenous prolactin treatment were evaluated. In lactating rats calcium absorption and plasma levels of parathyroid hormone, 1,25(OH)2D3 and alkaline phosphatase activity were significantly increased. Bromocriptine treatment significantly reduced the enhanced calcium absorption and levels of plasma 1,25(OH)2D3 and alkaline phosphatase but had no significant effect on plasma levels of parathyroid hormone. Prolactin administered with bromocriptine to lactating animals prevented all the changes observed with bromocriptine treatment alone. It was concluded that the increased plasma levels of prolactin during lactation lead to high plasma levels of 1,25(OH)2D3 which are responsible for the enhanced intestinal calcium absorption.

Published
1982
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