1. Video-assisted thoracoscopic surgery for ectopic mediastinal parathyroid adenoma.
- Author
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Isaacs KE, Belete S, Miller BJ, Di Marco AN, Kirby S, Barwick T, Tolley NS, Anderson JR, and Palazzo FF
- Subjects
- Adenoma complications, Adult, Choristoma complications, Conversion to Open Surgery statistics & numerical data, Female, Humans, Hyperparathyroidism, Primary etiology, Male, Mediastinal Neoplasms complications, Mediastinum surgery, Middle Aged, Operative Time, Parathyroidectomy adverse effects, Prospective Studies, Sternotomy statistics & numerical data, Thoracic Surgery, Video-Assisted adverse effects, Treatment Outcome, Adenoma surgery, Choristoma surgery, Hyperparathyroidism, Primary surgery, Mediastinal Neoplasms surgery, Parathyroid Glands, Parathyroidectomy methods, Thoracic Surgery, Video-Assisted methods
- Abstract
Background: Primary hyperparathyroidism (PHPT), caused by an ectopic mediastinal parathyroid adenoma, is uncommon. In the past, when the adenoma was not accessible from the neck, median sternotomy was advocated for safe and successful parathyroidectomy. Video-assisted thoracoscopic surgical (VATS) parathyroidectomy represents a modern alternative approach to this problem., Methods: Information on patients undergoing VATS was obtained from a specific database, including clinical presentation, biochemistry, preoperative imaging, surgical approach and patient outcomes. A comprehensive literature review was undertaken to draw comparisons with other publications., Results: Over a 2-year period, nine patients underwent VATS parathyroidectomy for sporadic PHPT. Five patients had persistent PHPT following previous unsuccessful parathyroidectomy via cervicotomy, and four had had no previous parathyroid surgery. The median duration of surgery was 90 (range 60-160) min. Eight patients were cured biochemically, with no major complications. One patient required conversion to a median sternotomy for removal of a thymoma that had resulted in false-positive preoperative imaging., Conclusion: With appropriate preoperative imaging, multidisciplinary input and expertise, VATS parathyroidectomy is an effective, safe and well tolerated approach to ectopic mediastinal parathyroid adenoma., (© 2019 The Authors. BJS Open published by John Wiley & Sons Ltd on behalf of BJS Society Ltd.)
- Published
- 2019
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