1. The relation between health-related quality of life, treatment adherence and disease severity in a paediatric sickle cell disease sample.
- Author
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Fisak B, Belkin MH, von Lehe AC, and Bansal MM
- Subjects
- Adaptation, Psychological, Adolescent, Anemia, Sickle Cell complications, Anemia, Sickle Cell physiopathology, Caregivers, Child, Child, Preschool, Female, Humans, Male, Pain complications, Pediatrics, Anemia, Sickle Cell psychology, Patient Compliance, Quality of Life
- Abstract
Background: The purpose of this study was to provide a comprehensive examination of the potential factors associated with health-related quality of life (HRQOL) in a paediatric sickle cell disease sample., Methods: Caregivers of 78 paediatric sickle cell disease patients completed surveys, which included measures of HRQOL, treatment adherence and barriers to treatment adherence. Medical chart reviews were also conducted to assess disease severity., Results: Barriers to treatment adherence and pain crisis frequency were found to be the most robust factors associated with HRQOL., Conclusions: This study provides insight into the factors related to paediatric sickle cell disease and informs both clinicians and researchers interested in understanding and improving HRQOL in this population. In particular, the reduction of pain crises frequency and barriers to adherence may be particularly effective strategies to improve HRQOL., (© 2011 Blackwell Publishing Ltd.)
- Published
- 2012
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