1. Occurrence of status epilepticus in persons with epilepsy is determined by sex, epilepsy classification, and etiology: a single center cohort study.
- Author
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Langenbruch, Lisa, Strippel, Christine, Görlich, Dennis, Elger, Christian E., Möddel, Gabriel, Meuth, Sven G., Kellinghaus, Christoph, Wiendl, Heinz, and Kovac, Stjepana
- Subjects
PEOPLE with epilepsy ,STATUS epilepticus ,EPILEPSY ,ETIOLOGY of diseases ,PARTIAL epilepsy ,PATIENT education - Abstract
Background: Status epilepticus (SE) can occur in persons with or without epilepsy and is associated with high morbidity and mortality. Methods: This survey aimed to record self-reported frequency of SE in persons with epilepsy, its association with clinical characteristics and patient level of information on SE and rescue medication. 251 persons with epilepsy at a tertiary epilepsy center were included in the study. Results: 87 (35%) had a history of SE defined as seizure duration of more than 5 min. These patients were less likely to be seizure-free, and had a higher number of present and past anti-seizure medication. Female sex, cognitive disability, younger age at epilepsy onset, defined epilepsy etiology, and focal epilepsy were associated with a history of SE. On Cox regression analysis, female sex, defined etiology and focal classification remained significant. 67% stated that they had information about prolonged seizures, and 75% knew about rescue medication. 85% found it desirable to receive information about SE at the time of initial diagnosis of epilepsy, but only 16% had been offered such information at the time. Conclusion: SE is frequent among persons with epilepsy and there remain unmet needs regarding patient education. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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