1. Are statins associated with decreased tooth loss in chronic periodontitis?
- Author
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Saver BG, Hujoel PP, Cunha-Cruz J, and Maupomé G
- Subjects
- Anti-Inflammatory Agents, Non-Steroidal therapeutic use, Chronic Disease, Dental Care statistics & numerical data, Epidemiologic Methods, Female, Humans, Male, Middle Aged, Periodontitis diagnosis, Smoking, Tooth Loss diagnosis, Tooth Loss etiology, Anticholesteremic Agents therapeutic use, Periodontitis complications, Tooth Loss prevention & control
- Abstract
Aim: To evaluate whether statin use was associated with decreased tooth loss among patients with chronic periodontitis., Material and Methods: We evaluated administrative health plan data from 1996 to 2002 covering dental and periodontal treatment utilization, dental extractions, and prescription medication fills of 12,631 adults aged 48-64 in 2002. With tooth loss as the outcome, we evaluated a number of different patterns of statin prescription across time in multivariate generalized linear models., Results: Unadjusted, statin use was associated with increased tooth loss. After adjustment for potential confounders, there was no suggestion of either increased or decreased tooth loss associated with statin use., Conclusions: Statin use was not associated with either a decreased or an increased risk of tooth loss.
- Published
- 2007
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