This article examines the lives of artefacts collected by physical anthropologist Aleš Hrdlička during his expeditions to Peru. In 1910 and 1913, Hrdlička travelled to the Andean nation to gather materials that could shed light on the peopling of the Americas, health and disease in pre-Columbian societies, and the purported racial ‘types' of the region. The study focuses on cultural artefacts the scientist acquired, beginning with these materials’ collection as specimens meant to reveal the racial prehistory of the Andes, and continuing with their classification, display, and exchange as museum objects at the Smithsonian Institution. My analysis of Hrdlička's Peruvian collection draws attention not only to how scientific representations of Peru and the Andes have shifted over time, but also to the way in which a focus on museum objects can elucidate changing notions about the cultural agency of prehistoric populations and their present-day descendants. [ABSTRACT FROM PUBLISHER]