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A visible‐light‐driven, copper‐catalyzed three‐component radical cross‐coupling of oxime esters, styrenes, and boronic acids has been developed. Key steps of this protocol involve catalytic generation of an iminyl radical from a redox‐active oxime ester and subsequent C−C bond cleavage to generate a cyanoalkyl radical. Upon its addition to styrene, the newly formed benzylic radical undergoes coupling with a boronic‐acid‐derived ArCuII complex to achieve 1,1‐diarylmethane‐containing alkylnitriles. Key steps of the visible‐light‐driven title reaction involve catalytic generation of an iminyl radical from a redox‐active oxime ester and subsequent C−C bond cleavage to give a cyanoalkyl radical. Upon its addition to styrene, a benzylic radical is formed that undergoes coupling with a boronic‐acid‐derived ArCuII complex to give 1,1‐diarylmethane‐containing alkylnitriles. The method features the use of readily available substrates and high functional‐group tolerance. [ABSTRACT FROM AUTHOR]

A visible-light-driven radical-mediated strategy for the in situ generation of aza- ortho-quinone methides from 2-vinyl-substituted anilines and alkyl radical precursors is described. This process enables an efficient multicomponent reaction of 2-vinylanilines, halides, and sulfur ylides, and has a wide substrate scope and good functional group tolerance. Treatment of the cycloaddition products with a base leads to densely functionalized indoles in a single-flask operation. [ABSTRACT FROM AUTHOR]

Neutral eosin Y‐derived photoexcited states have been found to serve as photoacids and direct hydrogen atom transfer (HAT) catalysts in the activation of glycals and C−H bonds, respectively. These studies pave the way for further use of eosin Y in photochemical synthesis. New sides of eosin Y: Neutral eosin Y‐derived photoexcited states have been found to serve as photoacids and direct hydrogen atom transfer (HAT) catalysts in the activation of glycals and C−H bonds, respectively. These studies pave the way for further use of eosin Y in photochemical synthesis. [ABSTRACT FROM AUTHOR]

A novel and efficient CP bond formation reaction of diarylphosphine oxides with aryl iodides was achieved by combining nickel catalysis and visible-light-induced photoredox catalysis. This dual-catalytic reaction showed a broad substrate scope, excellent functional group tolerance, and afforded the corresponding products in good to excellent yields. Compared with the previously reported use of photoredox/nickel dual catalysis in the construction of CC bonds, the methodology described herein was observed to be the first to allow for C-heteroatom bond formation. [ABSTRACT FROM AUTHOR]

An unprecedented α-allylation of amines was achieved by combining palladium catalysis and visible-light photoredox catalysis. In this dual catalysis process, the catalytic generation of allyl radical from the corresponding π-allylpalladium intermediate was achieved without additional metal reducing reagents (redox-neutral). Various allylation products of amines were obtained in high yields through radical cross-coupling under mild reaction conditions. Moreover, the transformation was applied to the formal synthesis of 8-oxoprotoberberine derivatives which show potential anticancer properties. [ABSTRACT FROM AUTHOR]

A visible-light-induced photocatalytic aerobic oxidation/ [3+2] cycloaddition/aromatization cascade between secondary amines and isocyanides has been successfully developed. The reaction provides a general and efficient access to diversely substituted imidazoles and imidazo[1,5- a]quinoxalin-4(5H)-ones in good yields under mild conditions. [ABSTRACT FROM AUTHOR]

A photocatalytic formal [3+2] cycloaddition of 2 H-azirines with alkynes has been achieved under irradiation by visible light in the presence of organic dye photocatalysts. This transformation provides efficient access to highly functionalized pyrroles in good yields and has been applied to the synthesis of drug analogues. A primary trial of photocascade catalysis merging energy transfer and redox neutral reactions was shown to be successful. [ABSTRACT FROM AUTHOR]

All lit up: A novel and efficient desulfonylation method of tosyl amides has been developed by means of visible ‐ light ‐ promoted reductive cleavage of NS bonds. This method has a broad substrate scope, good functional group tolerance, and excellent yields. [ABSTRACT FROM AUTHOR]

Visible-light photoredox catalysis has attracted tremendous interest within the synthetic community. As such, the activation mode potentially provides a more sustainable and efficient platform for the activation of organic molecules, enabling the invention of many controlled radical-involved reactions under mild conditions. In this context, amide synthesis via the strategy of photoredox catalysis has received growing interest due to the ubiquitous presence of this structural motif in numerous natural products, pharmaceuticals and functionalized materials. Employing this strategy, a wide variety of amides can be prepared effectively from halides, arenes and even alkanes under irradiation of visible light. These methods provide a robust alternative to well-established strategies for amide synthesis that involve condensation between a carboxylic acid and amine mediated by a stoichiometric activating agent. In this review, the representative progresses made on the synthesis of amides through visible light-mediated radical reactions are summarized. [ABSTRACT FROM AUTHOR]

Two birds with one stone: Recent advances in activating two reactants simultaneously using homogeneous visible‐light photoredox catalysis have been described. The conceptually new catalytic mode will aid in the design of some green and sustainable reactions. [ABSTRACT FROM AUTHOR]

The reaction tolerates variously functionalized aryl diazonium salts as well as terminal, 1,1- and cyclic or acyclic 1,2-disubstituted alkenes. [ABSTRACT FROM AUTHOR]

Review: 50 refs. [ABSTRACT FROM AUTHOR]

The article presents information on the synthesis of CF3-containing pyrazolines and isoxazolines through photocatalytic radical trifluoromethylation/cyclization cascade

A diagram is presented which shows chemical structures of photocatalytic oxytrifluoromethylation of N-allylamides for the synthesis of CF 3-containing benzoxazines and oxazoline.

Irradiation of solutions of β,γ-unsaturated hydrazones (I), (III), and (V) with blue light LEDs gives the corresponding pyrazoles (II), (IV), and (VI). [ABSTRACT FROM AUTHOR]

Review: 18 refs. [ABSTRACT FROM AUTHOR]

The dual-catalytic reaction between diarylphosphine oxides and aryl iodides shows good functional group tolerance and allows the synthesis of various triarylphosphine oxides. [ABSTRACT FROM AUTHOR]

The title reaction affords symmetrical and unsymmetrical 1,4-diketones which can be easily transformed into biologically valuable compounds [cf. [ABSTRACT FROM AUTHOR]

Review: 82 refs. [ABSTRACT FROM AUTHOR]

This is the first visible‐light‐induced (blue LED) radical alkoxycarboxylation of aryldiazonium salts using carbon monoxide gas. [ABSTRACT FROM AUTHOR]

An abstract of the article "De novo Synthesis of Imidazoles by Visible-Light-Induced Photocatalytic Aerobic Oxidation/[3 + 2] Cycloaddition/Aromatization Cascade" by Quiao-Hui Deng, You-Quan Zhou, Liang-Qui Lu, Zi-Long Tang, Jia-Rong Chen and Wen-Jing Xiao is presented.

This dual catalytic process is applied to a novel α-allylation of amines involving the reaction of an allyl radical from a π-allylpalladium complex and a α-amino radical which are generated in the same catalytic cycle. [ABSTRACT FROM AUTHOR]

The title synthesis provides an efficient access to highly functionalized pyrroles in good yields in the presence of organic dye photocatalyst. [ABSTRACT FROM AUTHOR]

The first example of sequence catalysis by merging visible light photoredox catalysis and nucleophilic catalysis is reported. [ABSTRACT FROM AUTHOR]