1. Isolation and genetic characterization of novel bovine parechoviruses from Japanese black cattle.
- Author
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Oba M, Shimotori M, Teshima N, Yamaguchi L, Takemae H, Sakaguchi S, Ishida H, Murakami H, Mizutani T, and Nagai M
- Subjects
- Animals, Cattle, 3' Untranslated Regions genetics, Japan, Genotype, Nucleic Acid Conformation, RNA, Viral genetics, Phylogeny, Parechovirus genetics, Parechovirus isolation & purification, Parechovirus classification, Picornaviridae Infections veterinary, Picornaviridae Infections virology, Feces virology, Cattle Diseases virology
- Abstract
Novel bovine parechoviruses (Bo ParVs) were isolated from the feces of Japanese black cattle. Phylogenetic analysis revealed that the novel Bo ParVs formed an independent cluster, exhibiting 72.2-75.6% nucleotide sequence identity to previous Bo ParVs, suggesting that they represent a new genotype. Bo ParVs, including the novel Bo ParVs, shared sequence similarity with each other in the 3' untranslated region (3'UTR) and exhibited low sequence similarity (<38.9% identity) to other parechoviruses. However, a secondary structure prediction of the 3'UTR revealed that the Bo ParVs shared conserved motifs in domain 2 with parechovirus B and E, suggesting some evolutionary constrains in this region., (© 2024. The Author(s).)
- Published
- 2024
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