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A chemical peel is chemexfoliation, a process of application of a chemical substance to the skin that causes controlled chemical destruction of the epidermis with or without part of the dermis leading to skin regeneration and remodeling. It can be classified depending upon the depth of penetration into superficial, medium, and deep peels. Among various indications, peels can be used to enhance treatment within a variety of conditions including skin- rejuvenation, inflammatory disorders like acne, rosacea, acne scar, and pigmentary disorders like melasma, freckles, lentigens, dyschromia, and post-inflammatory pigmentation. We did a chemical peel for six patients with facial melanosis, diagnosed with Riehl melanosis. All patients had visible clinical improvement. Detailed history and informed consent were taken both for photographs and procedures from all patients.

Henna is a vegetable hair dye that can be used by individuals who are sensitized to oxidative dyes due to low allergenicity. The reported incidence of slate-grey facial dyspigmentation following the use of henna hair dye is extremely rare. This study aimed to identify the clinical, dermoscopic, and histopathological features of slate-grey facial dyspigmentation following the use of henna hair dye in Korean patients. We identified all patients who presented with slate-grey facial dyspigmentation following usage of henna hair dye. Patients were further evaluated for clinical, dermoscopic, and histopathological findings along with their patch test results. All 11 patients were females with Fitzpatrick's skin phototype III or IV. Prominent slate-grey-coloured dyspigmentation on the lateral side of the face and neck was most common in eight (72%) patients. Under dermoscopic examination, a pseudo-network with grey dots was observed in all patients. Histopathological examination revealed liquefaction degeneration of the epidermal basal layer and pigmentary incontinence in the papillary dermis in all patients. The diagnosis of pigmented contact dermatitis following usage of henna was made based on the clinical, dermoscopic, and histopathological findings in all patients. Pigmented contact dermatitis associated with henna occurs mostly in middle-aged women and requires long-term treatment. Therefore, careful attention should be paid when henna is used to dye hair in this age group.

Eight patients suffering from pigmented contact dermatitis caused by the commercial Brilliant Lake Red R were patch tested with purified Sudan I and its several chemical analogues. Positive reactions were observed to Sudan I, Orange SS, Brilliant Lake Red R, Vacanceine Red, Yellow OB and Sudan II. Negative patch tests were obtained with Toluidine Red, Permanent Orange, Lithol Red and Sudan III. We found that the commercial Brilliant Lake Red R which had been said to be the most important causative agent of pigmented contact dermatitis, contained Sudan I as a major impurity. The patients reacting to Brilliant Lake Red R always gave a positive reaction to Sudan I, but those reacting to Sudan I did not always give a positive reaction to Brilliant Lake Red R. This suggests that Sudan I is a potent sensitizer and may induce contact sensitivity and that Brilliant Lake Red R itself is a weak sensitizer or a cross-reacting substance. [ABSTRACT FROM AUTHOR]

This article discusses a case study related to pigmented photoallergic contact dermatitis from musk ambrette. A 52-year-old male, working as a car driver, had 4-year old history of facial dermatitis. Only diffuse cutaneous brownish pigmentation restricted to the beard area was observed. Facial photosensitivity followed within few months, the use of a new after-shave lotion containing musk ambrette. This fragrance ingredient of male cosmetics is often reported as a cause of allergic or photoallergic contact dermatitis and sometimes persistent light reaction. Positive photopatch tests with residual pigmentation strongly suggest that musk ambrette present in the after-shave lotion was the agent of this pigmented photoallergic contact dermatitis.

The article presents a case study of a 54-year-old Spanish woman who presented with actiniclentigines on her arms and forearms, admitted to having used a fungal metabolic product Kojicol Plus for 5 years to lighten the lesions. She was patch tested with kojic acid 1% aqua and the Kojicol Plus, and the results were negative. However, the study reveals that in contact dermatitis, hyperpigmentation often occurs without any clinical dermatitis.