Search

This study evaluated the impact of silver particles, suspended in Arnica montana flower extract, on the physicochemical characteristics and release dynamics of antioxidant compounds in PVP (polyvinylpyrrolidone)-based hydrogel systems. The hydrogels were synthesized via photopolymerization with fixed amounts of crosslinker (PEGDA) and photoinitiator, while the concentration of the silver-infused extract was systematically varied. Key properties, including the density, porosity, surface roughness, swelling capacity, and water vapor transmission rate (WVTR), were quantitatively analyzed. The results demonstrated that increasing the silver content reduced the hydrogel density from 0.6669 g/cm 3 to 0.2963 g/cm 3 and increased the porosity from 4% to 11.04%. The surface roughness parameters (Ra) rose from 8.42 µm to 16.33 µm, while the WVTR increased significantly from 65.169 g/m 2 ·h to 93.772 g/m 2 ·h. These structural changes directly influenced the release kinetics of antioxidant compounds, with kinetic modeling revealing silver-dependent variations in the evaluated release mechanisms. This innovative approach of integrating silver particles and plant-derived antioxidants into hydrogels highlights a novel pathway for tailoring material properties. The observed enhanced porosity and moisture regulation underscore the hydrogels' potential for biomedical applications, particularly in wound care, where controlled moisture and antioxidant delivery are critical. These findings provide new insights into how silver particles modulate hydrogel structures and functionalities.

In recent years, the utilization of natural components has become crucial across various industries, including medicine. Particularly in biomedical contexts, hydrogel materials are of significant importance. Therefore, the objective of this research was to develop and analyze hydrogel materials infused with vitamin C. A key focus of this study was to conduct multiple syntheses with varying levels of vitamin C to explore the feasibility of creating materials with adjustable properties. The produced hydrogels underwent comprehensive physicochemical evaluation. The findings of this examination verified the correlation between the vitamin C content and the specific characteristics of the hydrogels. It was determined from these results that the samples displayed both sorptive and antioxidative capabilities, enabling their potential application in wound dressings or other biomedical uses. A notable benefit of these hydrogels is their adaptability, allowing for modifications to achieve desired attributes tailored to particular applications.