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Moringa oleifera Lam. (Moringa) plant, which belongs to the Moringaceae family, is an important crop in Asia and Africa. Moringa has been investigated for its health benefits, which are related to several bioactive components found in the plant, including flavonoids, vitamins, phenolic acids, isothiocyanates, saponins, and tannins. The leaves of moringa have been researched extensively and hence proven to be effective in various chronic illnesses such as insulin resistance, hypercholesterolemia, diabetes, cancer, nonalcoholic liver disease, high blood pressure, and general inflammation. Moringa includes a variety of dietary phytonutrients, notably flavonoids, the secondary plant metabolites which have health-enhancing effects, such as avoiding damage to normal cellular DNA and stimulating the death of cancer cells, therefore reducing the prevalence of non-communicable disorders (NCDs). Flavonoids are phenolic chemicals, which are plant elements that correlate to the non-energy portion of a person's diet. Flavonoids are often removed chemically using solvents and conventional techniques that, in addition to being costly, take a long time and have an impact on the bioactivity of these substances. As a consequence, there is no universally applicable extraction procedure, and each best practice is adapted to the specific plants involved. To be selective, an extraction technique must have combined an ideal solvent or mixture of solvents with an optimum procedure. In this study, we provide information on the improved and standardized extraction process from Moringa leaf extract concerning flavonoids and its good consequences on immune system efficacy that have been documented. [ABSTRACT FROM AUTHOR]