1. Intraocular extramedullary plasmacytoma in a cat.
- Author
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Michau TM, Proulx DR, Rushton SD, Olivry T, Dunston SM, Gilger BC, and Davidson MG
- Subjects
- Animals, Antineoplastic Agents therapeutic use, Blindness etiology, Blindness veterinary, Cat Diseases drug therapy, Cat Diseases pathology, Cats, Drug Therapy, Combination, Eye Injuries complications, Eye Injuries veterinary, Eye Neoplasms complications, Eye Neoplasms diagnosis, Lymphatic Metastasis, Male, Melphalan therapeutic use, Orbit Evisceration veterinary, Plasmacytoma complications, Plasmacytoma diagnosis, Prednisone therapeutic use, Cat Diseases diagnosis, Eye Neoplasms veterinary, Plasmacytoma veterinary
- Abstract
An 8-year-old, castrated male Domestic Short-haired cat was referred for evaluation of a possible intraocular neoplasm following previous ocular trauma. The eye was blind, and uveitis and an iridal mass were noted on examination. An enucleation was performed and the mandibular lymph node excised. Histopathologic examination revealed neoplastic proliferation of plasma cells in the iris and lymph node. No other evidence of disseminated disease was detected. This is the first case reported of an intraocular extramedullary plasmacytoma in the cat. The variation in clinical manifestations and potential association with multiple myeloma are not known at this time. Disseminated metastasis from a primary plasmacytoma of the uveal tract could also involve the bone marrow and be indistinguishable from multiple myeloma. Early enucleation, as in trauma-associated sarcomas, may be indicated to prevent metastasis. Periodic systemic evaluation for evidence of multiple myeloma should be performed.
- Published
- 2003
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