1. Clinical factors influencing corrected count increment.
- Author
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Shastry S and Chaudhary R
- Subjects
- Adolescent, Adult, Aged, Child, Child, Preschool, Female, Humans, Male, Middle Aged, Platelet Count instrumentation, Platelet Transfusion adverse effects, Prospective Studies, Young Adult, Platelet Count methods, Platelet Transfusion methods, Plateletpheresis methods
- Abstract
Refractoriness to platelet transfusions is a common clinical problem. The present study was conducted to look into patient characteristics affecting the corrected count increment in a tertiary care referral hospital. A total of 161 aphaeresis platelet units were transfused to 40 patients with varied clinical diagnoses. The mean platelet increment was 17,789/mm(3). Median corrected count increment was 7344 and percentage platelet recovery was 22.82%. Logistic regression analysis revealed significant influence of splenomegaly and anti-platelet drugs on refractoriness. Fever, bleeding, sepsis, disseminated intravascular coagulation and cyclosporine use, though more common in the patients with refractoriness they were not statistically significant., (Copyright © 2012 Elsevier Ltd. All rights reserved.)
- Published
- 2012
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