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1,179 results on '"polyketide synthase"'

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1. Six type-I PKS classes and highly conserved melanin and elsinochrome gene clusters found in diverse Elsinoë species.

2. Evidence that the StlA polyketide synthase is required for the transition of growth to development in Polysphondylium violaceum.

3. Recent Advances in Discovery, Structure, Bioactivity, and Biosynthesis of trans -AT Polyketides.

4. Cryo-electron microscopy structure of the di-domain core of Mycobacterium tuberculosis polyketide synthase 13, essential for mycobacterial mycolic acid synthesis.

5. Structural insights into type III polyketide synthase CylI from cylindrocyclophane biosynthesis.

6. Reprogramming of the Aurantinin Polyketide Assembly Line to Synthesize Auritriacids by Excising an Atypical Enoyl-CoA Hydratase Domain.

7. Two Polyketide Synthase Genes, VpPKS10 and VpPKS33 , Regulated by VpLaeA Are Essential to the Virulence of Valsa pyri .

8. Structure and Mechanisms of Assembly-Line Polyketide Synthases.

9. Revealing Hidden Genes in Botrytis cinerea : New Insights into Genes Involved in the Biosynthesis of Secondary Metabolites.

10. Modifications of Protein-Bound Substrates by Trans-Acting Enzymes in Natural Products Biosynthesis.

11. Biosynthesis of Octacosamicin A: Uncommon Starter/extender Units and Product Releasing via Intermolecular Amidation.

12. Polyketide Synthase 13 (Pks13) Inhibition: A Potential Target for New Class of Anti-tubercular Agents.

13. Structure of a modular polyketide synthase reducing region.

14. Genomic mining and diversity of assembly line polyketide synthases.

15. Metagenomic data reveals type I polyketide synthase distributions across biomes.

16. Architecture of a PKS-NRPS hybrid megaenzyme involved in the biosynthesis of the genotoxin colibactin.

17. Iterative-Acting Thioesterase from Polyketide Biosynthesis Accepts Diverse Nucleophilic Alcohols to Yield Oxazole-Containing Esters.

18. An updated catalogue of diverse type II polyketide synthase biosynthetic gene clusters captured from large-scale nucleotide databases.

19. Function of the Polyketide Synthase Domains of Schizochytrium sp. on Fatty Acid Synthesis in Yarrowia lipolytica .

20. A polyketide synthase from Verticillium dahliae modulates melanin biosynthesis and hyphal growth to promote virulence.

21. Heterologous Expression, Purification, and Characterization of Type II Polyketide Synthase Acyl Carrier Proteins.

22. Biochemistry-Guided Prediction of the Absolute Configuration of Fungal Reduced Polyketides.

23. GRINS: Genetic elements that recode assembly-line polyketide synthases and accelerate their diversification.

24. Docking domain-mediated subunit interactions in natural product megasynth(et)ases.

25. Vital roles of Pks11, a highly reducing polyketide synthase, in fungal conidiation, antioxidant activity, conidial cell wall integrity, and UV tolerance of Beauveria bassiana.

26. Engineering the acyltransferase domain of epothilone polyketide synthase to alter the substrate specificity.

27. Site-Directed Mutagenesis of Modular Polyketide Synthase Ketoreductase Domains for Altered Stereochemical Control.

28. Optimizing Eicosapentaenoic Acid Production by Grafting a Heterologous Polyketide Synthase Pathway in the Thraustochytrid Aurantiochytrium .

29. A polyketide synthase HglE A , but not HglE2, synthesizes heterocyst specific glycolipids in Anabaena sp. PCC 7120.

30. Transcriptome survey and toxin measurements reveal evolutionary modification and loss of saxitoxin biosynthesis genes in the dinoflagellates Amphidinium carterae and Prorocentrum micans.

31. Loss of the Polyketide Synthase StlB Results in Stalk Cell Overproduction in Polysphondylium violaceum.

32. Unraveling the iterative type I polyketide synthases hidden in Streptomyces .

33. Employing 25-Residue Docking Motifs from Modular Polyketide Synthases as Orthogonal Protein Connectors.

34. Synthesis of Three Bioactive Aromatic Compounds by Introducing Polyketide Synthase Genes into Engineered Escherichia coli .

35. Biosynthesis of Long Chain Alkyl Diols and Long Chain Alkenols in Nannochloropsis spp. (Eustigmatophyceae).

36. Zebrafish otolith biomineralization requires polyketide synthase.

37. Probing the modularity of megasynthases by rational engineering of a fatty acid synthase Type I.

38. Cloning, expression, and purification of intact polyketide synthase modules.

39. Repurposing type III polyketide synthase as a malonyl-CoA biosensor for metabolic engineering in bacteria.

40. Flexible enzymatic activation of artificial polyketide extender units by Streptomyces cinnamonensis into the monensin biosynthetic pathway.

41. Diversity and evolution of polyketide biosynthesis gene clusters in the Ceratocystidaceae.

42. The Structural Enzymology of Iterative Aromatic Polyketide Synthases: A Critical Comparison with Fatty Acid Synthases.

43. PKS-NRPS Enzymology and Structural Biology: Considerations in Protein Production.

44. Both modular and single-domain Type I polyketide synthases are expressed in the brevetoxin-producing dinoflagellate, Karenia brevis (Dinophyceae).

45. Improved PKS Gene Expression With Strong Endogenous Promoter Resulted in Geldanamycin Yield Increase.

46. Genetic Mapping and Biochemical Basis of Yellow Feather Pigmentation in Budgerigars.

47. RNAi-mediated down-regulation of a melanin polyketide synthase (pks1) gene in the fungus Slafractonia leguminicola.

48. Evolution of polyketide synthesis in a Dothideomycete forest pathogen.

49. Polyketide mimetics yield structural and mechanistic insights into product template domain function in nonreducing polyketide synthases.

50. Insights into Substrate Modification by Dehydratases from Type I Polyketide Synthases.

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