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Your search keyword '"Farooqi, Lubna"' showing total 3 results
Start Over Author "Farooqi, Lubna" Topic polymerase chain reaction
3 results on '"Farooqi, Lubna"'

1. Sensitivity of Nasopharyngeal Swabs and Saliva for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2

Author

Jamal, Alainna J, Mozafarihashjin, Mohammad, Coomes, Eric, Powis, Jeff, Li, Angel X, Paterson, Aimee, Anceva-Sami, Sofia, Barati, Shiva, Crowl, Gloria, Faheem, Amna, Farooqi, Lubna, Khan, Saman, Prost, Karren, Poutanen, Susan, Taylor, Maureen, Yip, Lily, Zhong, Xi Zoe, McGeer, Allison J, Mubareka, Samira, Coleman, Brenda L, Chen, Danny, Farshait, Nataly, Gold, Wayne, Kandel, Christopher E, Katz, Kevin, Kozak, Robert, Mazzulli, Tony, Muller, Matthew, Opavsky, Anne, Ostrowski, Mario, Plevneshi, Agron, Rau, Neil, Ricciuto, Daniel, Richardson, David, Rose, David, Sales, Valerie, and Walmsley, Sharon

Subjects
0301 basic medicine, Microbiology (medical), medicine.medical_specialty, Saliva, Canada, Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), 030106 microbiology, Saliva sample, medicine.disease_cause, Real-Time Polymerase Chain Reaction, Gastroenterology, law.invention, 03 medical and health sciences, 0302 clinical medicine, stomatognathic system, law, Internal medicine, Nasopharynx, medicine, Humans, 030212 general & internal medicine, Polymerase chain reaction, Coronavirus, saliva, business.industry, SARS-CoV-2, Brief Report, COVID-19, nasopharyngeal swab, Reverse transcriptase, 3. Good health, Real-time polymerase chain reaction, Infectious Diseases, AcademicSubjects/MED00290, business
Abstract

We enrolled 91 consecutive inpatients with COVID-19 at 6 hospitals in Toronto, Canada, and tested 1 nasopharyngeal swab/saliva sample pair from each patient using real-time RT-PCR for severe acute respiratory syndrome coronavirus 2. Sensitivity was 89% for nasopharyngeal swabs and 72% for saliva (P = .02). Difference in sensitivity was greatest for sample pairs collected later in illness.

Published
2020

2. Household Transmission of Carbapenemase-producing Enterobacterales in Ontario, Canada.

Author

Jamal, Alainna J, Faheem, Amna, Farooqi, Lubna, Zhong, Xi Zoe, Armstrong, Irene, Boyd, David A, Borgundvaag, Emily, Coleman, Brenda L, Green, Karen, Jayasinghe, Kithsiri, Johnstone, Jennie, Katz, Kevin, Kohler, Philipp, Li, Angel X, Mataseje, Laura, Melano, Roberto, Muller, Matthew P, Mulvey, Michael R, Nayani, Sarah, and Patel, Samir N

Subjects
HOME environment, PUBLIC health surveillance, HOST-bacteria relationships, CONFIDENCE intervals, MULTIPLE regression analysis, ENTEROBACTERIACEAE diseases, INTERVIEWING, INFECTIOUS disease transmission, DESCRIPTIVE statistics, CARBAPENEMS, POLYMERASE chain reaction, ODDS ratio
Abstract

Background Data on household transmission of carbapenemase-producing Enterobacterales (CPE) remain limited. We studied risk of CPE household co-colonization and transmission in Ontario, Canada. Methods We enrolled CPE index cases (identified via population-based surveillance from January 2015 to October 2018) and their household contacts. At months 0, 3, 6, 9, and 12, participants provided rectal and groin swabs. Swabs were cultured for CPE until September 2017, when direct polymerase chain reaction (PCR; with culture of specimens if a carbapenemase gene was detected) replaced culture. CPE risk factor data were collected by interview and combined with isolate whole-genome sequencing to determine likelihood of household transmission. Risk factors for household contact colonization were explored using a multivariable logistic regression model with generalized estimating equations. Results Ninety-five households with 177 household contacts participated. Sixteen (9%) household contacts in 16 (17%) households were CPE-colonized. Household transmission was confirmed in 3/177 (2%) cases, probable in 2/177 (1%), possible in 9/177 (5%), and unlikely in 2/177 (1%). Household contacts were more likely to be colonized if they were the index case's spouse (odds ratio [OR], 6.17; 95% confidence interval [CI], 1.05–36.35), if their index case remained CPE-colonized at household enrollment (OR, 7.00; 95% CI, 1.92–25.49), or if they had at least 1 set of specimens processed after direct PCR was introduced (OR, 6.46; 95% CI, 1.52–27.40). Conclusions Nine percent of household contacts were CPE-colonized; 3% were a result of household transmission. Hospitals may consider admission screening for patients known to have CPE-colonized household contacts. [ABSTRACT FROM AUTHOR]

Published
2021
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3. Sensitivity of Nasopharyngeal Swabs and Saliva for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2.

Author

Jamal, Alainna J, Mozafarihashjin, Mohammad, Coomes, Eric, Powis, Jeff, Li, Angel X, Paterson, Aimee, Anceva-Sami, Sofia, Barati, Shiva, Crowl, Gloria, Faheem, Amna, Farooqi, Lubna, Khan, Saman, Prost, Karren, Poutanen, Susan, Taylor, Maureen, Yip, Lily, Zhong, Xi Zoe, McGeer, Allison J, Mubareka, Samira, and Investigators, Toronto Invasive Bacterial Diseases Network COVID-19

Subjects
SALIVA analysis, HOSPITALS, COVID-19, NOSE, DESCRIPTIVE statistics, COLLECTION & preservation of biological specimens, POLYMERASE chain reaction
Abstract

We enrolled 91 consecutive inpatients with COVID-19 at 6 hospitals in Toronto, Canada, and tested 1 nasopharyngeal swab/saliva sample pair from each patient using real-time RT-PCR for severe acute respiratory syndrome coronavirus 2. Sensitivity was 89% for nasopharyngeal swabs and 72% for saliva (P  = .02). Difference in sensitivity was greatest for sample pairs collected later in illness. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

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