7 results on '"Stegarescu, Adina"'
Search Results
2. Correlation of Elemental Transfer, Bioactive Compounds and Antioxidant Activity on Lactuca sativa L. Grown in Soil with Functionalized CNT and HMs.
- Author
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Soran, Maria-Loredana, Lung, Ildiko, Stegarescu, Adina, Culicov, Otilia, Opriș, Ocsana, Nekhoroshkov, Pavel, and Podar, Dorina
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LETTUCE ,BIOACTIVE compounds ,CARBON nanotubes ,SOILS ,COPPER ,TRACE metals - Abstract
While heavy metals (HM) have been considered in recent decades to be the most common and problematic pollutants, the expansion of the list of pollutants due to the active use of carbon nanotubes (CNT) raises new questions about the benefit and harm of HM released to nature individually or fixed on CNT walls. A pot experiment was conducted to compare the effect of two classes of potential pollutants—metal salts of Pb, Mn, Cu, Zn, Cd, and Ni; and functionalized CNTs with COOH, MnO
2 , Fe3 O4 , and MnO2 -Fe3 O4 —applied in soil, on the elemental transfer, the bioactive compounds accumulation, and the antioxidant activity in lettuce. While CNTs mainly increased the elemental transfer from soil to leaves, HM salts strongly obstructed it. In the presence of CNTs, the antioxidant activity in lettuce leaves correlated with the transfer of elements from soil to root and from root to leaves. The excess of HMs in soil induced a greater variation of the polyphenols quantity and antioxidant activity than the excess of CNTs. It might be assumed that lettuce perceived HMs as a more aggressive stressor than CNTs and more strongly activated the defense mechanism, showing the reduction of the element transfer and enhancing of total polyphenol production and antioxidant activity. [ABSTRACT FROM AUTHOR]- Published
- 2023
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3. Antioxidant, Anti-Inflammatory Effects and Ability to Stimulate Wound Healing of a Common-Plantain Extract in Alginate Gel Formulations.
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Bâldea, Ioana, Lung, Ildiko, Opriş, Ocsana, Stegarescu, Adina, Kacso, Irina, and Soran, Maria-Loredana
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ANTIOXIDANTS ,WOUND healing ,ALGINATES ,SPECTROPHOTOMETRY ,ENZYME-linked immunosorbent assay - Abstract
Our study aimed to investigate the biological effects of a common-plantain (Plantago major L.) extract, encapsulated in alginate, on dermal human fibroblast cultures in vitro, in view of its potential use as a wound healing adjuvant therapy. Common-plantain extracts were obtained by infusion and ultrasound extraction, and their total polyphenolic content and antioxidant capacity were determined by spectrophotometry. The best extract, which was obtained by infusion, was further encapsulated in sodium alginate in two different formulations. Fourier Transform Infrared Spectroscopy (FTIR) was used to demonstrate the existing interactions in the obtained common-plantain extract in the alginate formulations. The encapsulation efficiency was evaluated based on the total polyphenol content. These alginate gel formulations were further used in vitro to determine their biocompatibility and antioxidant and anti-inflammatory effects by spectrophotometry and ELISA, as well as their ability to stimulate fibroblast migration (scratch test assay) at different time points. In addition, the collagen 1 and 3 levels were determined by Western blot analysis. The data showed that the microencapsulated plantain extract formulations induced an antioxidant, anti-inflammatory effect, enhanced collagen production and increased wound closure in the first 8 h of their application. These results are encouraging for the use of this alginate plantain extract formulation as an adjuvant for skin wound healing. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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4. Biosynthesis of Nanoparticles Using Plant Extracts and Essential Oils.
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Antunes Filho, Sérgio, dos Santos, Mayara Santana, dos Santos, Otávio Augusto L., Backx, Bianca Pizzorno, Soran, Maria-Loredana, Opriş, Ocsana, Lung, Ildiko, Stegarescu, Adina, and Bououdina, Mohamed
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PLANT extracts ,PLANT products ,ESSENTIAL oils ,POISONS ,NANOPARTICLES ,VEGETABLE oils ,NANOSTRUCTURED materials - Abstract
Plant extracts and essential oils have a wide variety of molecules with potential application in different fields such as medicine, the food industry, and cosmetics. Furthermore, these plant derivatives are widely interested in human and animal health, including potent antitumor, antifungal, anti-inflammatory, and bactericidal activity. Given this diversity, different methodologies were needed to optimize the extraction, purification, and characterization of each class of biomolecules. In addition, these plant products can still be used in the synthesis of nanomaterials to reduce the undesirable effects of conventional synthesis routes based on hazardous/toxic chemical reagents and associate the properties of nanomaterials with those present in extracts and essential oils. Vegetable oils and extracts are chemically complex, and although they are already used in the synthesis of nanomaterials, limited studies have examined which molecules are effectively acting in the synthesis and stabilization of these nanostructures. Similarly, few studies have investigated whether the molecules coating the nanomaterials derived from these extracts and essential oils would bring benefits or somehow reduce their potential activity. This synergistic effect presents a promising field to be further explored. Thus, in this review article, we conducted a comprehensive review addressing the main groups of molecules present in plant extracts and essential oils, their extraction capacity, and available methodologies for their characterization. Moreover, we highlighted the potential of these plant products in the synthesis of different metallic nanomaterials and their antimicrobial capacity. Furthermore, we correlated the extract's role in antimicrobial activity, considering the potential synergy between molecules from the plant product and the different metallic forms associated with nanomaterials. [ABSTRACT FROM AUTHOR]
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- 2023
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5. A Multi-Method Approach for Impact Assessment of Some Heavy Metals on Lactuca sativa L.
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Soran, Maria-Loredana, Sîrb, Aura Nicoleta, Lung, Ildiko, Opriş, Ocsana, Culicov, Otilia, Stegarescu, Adina, Nekhoroshkov, Pavel, and Gligor, Delia-Maria
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LETTUCE ,BIOACTIVE compounds ,PHOTOSYNTHETIC pigments ,COPPER ,POLLUTANTS ,PLANT polyphenols ,HEAVY metals ,POLYPHENOLS - Abstract
Heavy metals represent a large category of pollutants. Heavy metals are the focus of researchers around the world, mainly due to their harmful effects on plants. In this paper, the influence of copper, cadmium, manganese, nickel, zinc and lead, present in soil in different concentrations (below the permissible limit, the maximum permissible concentration and a concentration higher than the maximum permissible limit) on lettuce (Lactuca sativa L.) was evaluated. For this purpose, the authors analyzed the variation of photosynthetic pigments, total polyphenols, antioxidant activity and the elemental content in the studied plants. The experimental results showed that the variation of the content of biologically active compounds, elemental content and the antioxidant activity in the plants grown in contaminated soil, compared to the control plants, depends on the type and concentration of the metal added to the soil. The biggest decrease was recorded for plants grown in soil treated with Ni I (−42.38%) for chlorophyll a, Zn II (−32.92%) for chlorophyll b, Ni I (−40.46%) for carotenoids, Pb I (−40.95%) for polyphenols and Cu III (−29.42%) for DPPH. On the other hand, the largest increase regarding the amount of biologically active compounds was registered for Mn I (88.24%) in the case of the chlorophyll a, Mn I (65.56%) for chlorophyll b, Pb I (116.03%) for carotenoids, Ni III (1351.23%) for polyphenols and Ni III (1149.35%) for DPPH. [ABSTRACT FROM AUTHOR]
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- 2023
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6. The Effect of Copper Salts on Bioactive Compounds and Ultrastructure of Wheat Plants.
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Culicov, Otilia, Stegarescu, Adina, Soran, Maria-Loredana, Lung, Ildiko, Opriș, Ocsana, Ciorîță, Alexandra, and Nekhoroshkov, Pavel
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COPPER salts , *BIOACTIVE compounds , *PLANT ultrastructure , *POLYPHENOLS , *METABOLITES , *ABIOTIC stress - Abstract
Abiotic stress agents, among them metal stress, can cause oxidative damage to plant cells. In defense, plants can increase the production of secondary metabolites in order to mitigate the harmful effects caused by them. The purpose of this work was to evaluate the effect of two types of copper salts (CuSO4 and Cu(NO3)2), added in two different amounts in soil (150 mg/kg, respectively 300 mg/kg), on assimilating pigments, total polyphenols, antioxidant activity and the elemental composition of wheat. The obtained results were compared with those from control plants grown in the same conditions but without copper salts. The amount of assimilating pigments, total polyphenols, and antioxidant activity respectively increases or decreases in the plants treated with copper salts compared to the control depending on the stage of development of the plant. No significant damage induced in the leaves of the wheat plants treated with the selected salts was observed following the TEM analysis. In six-week-old plants it was observed by EDX analysis that the salts are transformed into nanoparticles. The bioactive compounds, elemental composition and their interaction is influenced by concentration of metal's salt, type of salt and exposure period. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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7. The Effect of TiO 2 Nanoparticles on the Composition and Ultrastructure of Wheat.
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Soran, Maria-Loredana, Lung, Ildiko, Opriș, Ocsana, Culicov, Otilia, Ciorîță, Alexandra, Stegarescu, Adina, Zinicovscaia, Inga, Yushin, Nikita, Vergel, Konstantin, Kacso, Irina, and Borodi, Gheorghe
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POLYPHENOLS ,TITANIUM dioxide ,WHEAT ,PLANT polyphenols ,OXIDANT status ,TRANSMISSION electron microscopy ,WHEAT farming ,BIOCHAR - Abstract
The present work aims to follow the influence of TiO
2 nanoparticles (TiO2 NPs) on bioactive compounds, the elemental content of wheat, and on wheat leaves' ultrastructure. Synthesized nanoparticles were characterized by X-ray diffraction (XRD), Fourier transform infrared (FT-IR) spectroscopy, and transmission electron microscopy (TEM). The concentration of phenolic compounds, assimilation pigments, antioxidant capacity, elemental content, as well as the ultrastructural changes that may occur in the wheat plants grown in the presence or absence of TiO2 NPs were evaluated. In plants grown in the presence of TiO2 NPs, the amount of assimilating pigments and total polyphenols decreased compared to the control sample, while the antioxidant activity of plants grown in amended soil was higher than those grown in control soil. Following ultrastructural analysis, no significant changes were observed in the leaves of TiO2 -treated plants. Application of TiO2 NPs to soil caused a significant reaction of the plant to stress conditions. This was revealed by the increase of antioxidant capacity and the decrease of chlorophyll, total polyphenols, and carotenoids. Besides, the application of TiO2 NPs led to significant positive (K, Zn, Br, and Mo) and negative (Na, Mn, Fe, As, Sr, Sb, and Ba) variation of content. [ABSTRACT FROM AUTHOR]- Published
- 2021
- Full Text
- View/download PDF
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