1. Chiral Metal-Organic Frameworks Bearing Free Carboxylic Acids for Organocatalyst Encapsulation.
- Author
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Liu, Yan, Xi, Xiaobing, Ye, Chengcheng, Gong, Tengfei, Yang, Zhiwei, and Cui, Yong
- Subjects
CARBOXYLIC acids ,ENCAPSULATION (Catalysis) ,METAL-organic frameworks ,CHIRALITY ,POROSITY ,ALDOLS - Abstract
Two chiral carboxylic acid functionalized micro- and mesoporous metal-organic frameworks (MOFs) are constructed by the stepwise assembly of triple-stranded heptametallic helicates with six carboxylic acid groups. The mesoporous MOF with permanent porosity functions as a host for encapsulation of an enantiopure organic amine catalyst by combining carboxylic acids and chiral amines in situ through acid-base interactions. The organocatalyst-loaded framework is shown to be an efficient and recyclable heterogeneous catalyst for the asymmetric direct aldol reactions with significantly enhanced stereoselectivity in relative to the homogeneous organocatalyst. [ABSTRACT FROM AUTHOR]
- Published
- 2014
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