15 results on '"Baumgartner, Jeannine"'
Search Results
2. Nutrition during pregnancy and early development (NuPED) in urban South Africa: a study protocol for a prospective cohort
- Author
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Symington, Elizabeth A., Baumgartner, Jeannine, Malan, Linda, Zandberg, Lizelle, Ricci, Cristian, and Smuts, Cornelius M.
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- 2018
- Full Text
- View/download PDF
3. Iodine status of pregnant women residing in the urban Free State Province of South Africa is borderline adequate: The NuEMI study.
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Ngounda, Jennifer, Baumgartner, Jeannine, Nel, Mariette, and Walsh, Corinna May
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CROSS-sectional method , *PREGNANT women , *QUESTIONNAIRES , *DESCRIPTIVE statistics , *IODINE , *RURAL population , *PREGNANCY - Abstract
Adequate iodine nutrition during pregnancy is essential for optimal fetal development and neonatal outcomes. In South Africa, the iodine status of pregnant women, who have increased iodine requirements, is under-researched. We hypothesized that the iodine status of pregnant women in the Free State Province would be inadequate and may differ between urban and rural areas. This cross-sectional study included 430 urban and 187 rural pregnant women visiting antenatal clinics in the Free State. Urinary iodine concentration (UIC) was determined using the modified Sandell‐Kolthoff reaction method, and serum thyroglobulin (Tg) was measured using the Q-Plex™ Human Micronutrient Array. Data on self-reported iodized salt use were collected using a questionnaire. Median (IQR) UIC was 155 (96-248) µg/L; 150 (94-235) µg/L in urban and 161 (106-256) µg/L in rural participants (P = 0.27), indicative of adequate iodine status. Median (IQR) Tg was 11.5 (7.1-20.4) µg/L, and was not significantly associated with UIC, even after controlling for maternal age and gestational age (urban P = 0.14; rural P = 0.48). The proportions of pregnant women who reported to use iodized household salt were 81% in urban and 70% in rural areas. Our results show that despite the widespread use of iodized salt, the median UIC of pregnant women residing in the urban Free State Province indicates only borderline adequate iodine status. A national iodine survey including pregnant women is recommended to determine the effectiveness of the South African salt iodization program in light of the current salt reduction policy. Assessment of the iodine status in pregnant women residing in the urban and rural areas of the Free State Province, South Africa. [Display omitted] [ABSTRACT FROM AUTHOR]
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- 2022
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4. Iodine status of pregnant women living in urban Johannesburg, South Africa.
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Siro, Sicelosethu S., Zandberg, Lizelle, Ngounda, Jennifer, Wise, Amy, Symington, Elizabeth A., Malan, Linda, Smuts, Cornelius M., and Baumgartner, Jeannine
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THYROTROPIN ,KRUSKAL-Wallis Test ,PREGNANCY & psychology ,THYROXINE ,CROSS-sectional method ,RESEARCH methodology ,ANTHROPOMETRY ,INTERVIEWING ,GESTATIONAL age ,CITY dwellers ,PSYCHOSOCIAL factors ,RESEARCH funding ,DESCRIPTIVE statistics ,ANALYSIS of covariance ,MATERNAL age ,URINALYSIS ,GLOBULINS ,METROPOLITAN areas ,DATA analysis software ,IODINE ,PREGNANCY - Abstract
Adequate intake of iodine is important during pregnancy because of its essential role in foetal growth and neurodevelopment. Data on iodine status of South African pregnant women are scarce, and the salt reduction policy implemented in 2016 may decrease iodine intake of South Africans. This cross‐sectional study assessed the iodine status of pregnant women residing in urban Johannesburg, South Africa. A total of 250 pregnant women were enrolled into the 'Nutrition during Pregnancy and Early Development' (NuPED) study and 312 pregnant women into the 'Assessment of dried blood spot thyroglobulin in pregnant women to redefine the range of median urinary iodine concentration that indicates adequate iodine intake, South Africa' (STRIPE‐SA) study and were included in this analysis. Urinary iodine concentration (UIC) was analysed in a spot urine sample. Thyroglobulin (Tg) was measured in serum, and thyroid‐stimulating hormone (TSH) and total thyroxine (tT4) were measured in dried blood spots. The median [interquartile range (IQR)] UIC of pregnant women was 144 (84–234) μg/L. Women in the first (n = 99), second (n = 262) and third (n = 174) trimester had a median UIC of 133 (81–316), 145 (84–236) and 156 (89–245) μg/L, respectively (p = 0.419). Median TSH, tT4 and Tg were 2.7 (2.3–3.2) mU/L, 202 (163–236) nmol/L and 9.2 (5.4–17.9) μg/L, respectively. Based on the median UIC, pregnant women residing in urban Johannesburg may be borderline iodine deficient. These findings highlight the need for ongoing monitoring of iodine status among vulnerable pregnant women, especially considering the recently introduced salt reduction policy in South Africa. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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- View/download PDF
5. Maternal iron-deficiency is associated with premature birth and higher birth weight despite routine antenatal iron supplementation in an urban South African setting: The NuPED prospective study.
- Author
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Symington, Elizabeth A., Baumgartner, Jeannine, Malan, Linda, Wise, Amy J., Ricci, Cristian, Zandberg, Lizelle, and Smuts, Cornelius M.
- Subjects
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IRON supplements , *PREMATURE labor , *BIRTH weight , *PREGNANT women , *LONGITUDINAL method , *IRON deficiency anemia - Abstract
Background: Recent studies are suggesting a U-shaped relationship between antenatal iron exposure and birth outcomes. Little is known about the iron status and associated birth outcomes of pregnant women in South Africa. Our aim was to assess iron status at early, mid- and late pregnancy, and to determine associations with gestational age and birth weight in women in Johannesburg, South Africa. Methods: In this prospective study of 250 pregnant women, we measured haemoglobin, biomarkers of iron status and inflammation at <18, 22 and 36 weeks of gestation, plus birth weight and gestational age at delivery. Associations of anaemia and iron status with birth outcomes were determined using regression models adjusted for confounders. Results: At enrolment, the prevalence of anaemia, iron depletion (ID) and iron deficiency erythropoiesis (IDE) was 29%, 15% and 15%, respectively, and increased significantly with pregnancy progression. Anaemia and ID at 22 weeks, as well as IDE at 36 weeks were associated with higher birth weight (β = 135.4; 95% CI: 4.8, 266.1 and β = 205.4; 95% CI: 45.6, 365.1 and β = 178.0; 95% CI: 47.3, 308.7, respectively). Women in the lowest ferritin quartile at 22 weeks gave birth to babies weighing 312 g (95% CI: 94.8, 528.8) more than those in the highest quartile. In contrast, IDE at 22 weeks was associated with a higher risk for premature birth (OR: 3.57, 95% CI: 1.24, 10.34) and women in lower haemoglobin quartiles at <18 weeks had a shorter gestation by 7 days (β = -6.9, 95% CI: -13.3, -0.6) compared to those in the highest quartile. Conclusion: Anaemia, ID and IDE prevalence increased during pregnancy despite routine iron supplementation. ID and anaemia at mid-pregnancy were associated with higher birth weight, while IDE was associated with premature birth. These results suggest that current antenatal screening and supplementation practices in South Africa need to be revisited. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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6. Higher n-3 polyunsaturated fatty acid status during early pregnancy is associated with lower risk for depression at 12 months postpartum: The NuPED study.
- Author
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Osuna, Ester, Symington, Elizabeth A, Malan, Linda, Ricci, Cristian, Zandberg, Lizelle, Smuts, Cornelius M, and Baumgartner, Jeannine
- Abstract
• Higher red blood cell (RBC) DHA and n-3 index were associated with lower odds for depression at 12 months postpartum. • Higher n-6/n-3 PUFA and AA/EPA ratios at early pregnancy were associated with higher odds for depression at 12 months postpartum. • Women with higher RBC n-3 PUFA status during early pregnancy may be at lower risk for depression at 12 months postpartum. Perinatal depression can negatively affect the health of the mother and her offspring. N-3 polyunsaturated fatty acids (PUFA) may play a role in the aetiology of depression. Therefore, we investigated the association of n-3 PUFA status during early pregnancy with perinatal depression among women living in urban Johannesburg, South Africa. For this prospective analysis, we analysed red blood cell (RBC) total phospholipid fatty acid (FA) composition (% of total FA) of 242 pregnant women at < 18 weeks' gestation. We used the Edinburgh Postnatal Depression Scale (EPDS) to identify women at risk for depression (EPDS score ≥ 9) at < 18, 22 and 36 weeks' gestation, and at 6 and 12 months postpartum. RBC EPA status was negatively (β =-0.22, p < 0.05), and the AA/EPA ratio positively (β =0.24, p < 0.05) associated with EPDS scores at 12 months postpartum. Higher RBC DHA and n-3 index were further associated with lower odds (OR=0.56 [95% CI: 0.32-0.91]; OR=0.63 [95% CI: 0.39-0.94]), while higher n-6/n-3 PUFA and AA/EPA ratios early in pregnancy were associated with higher odds for depression at 12 months postpartum ((OR=2.34 [95% CI: 1.12-4.97]; OR=1.02 [95% CI: 1.00-1.05]). Our results suggest that women with a higher RBC n-3 PUFA status during early pregnancy may be at lower risk for depression at 12 months postpartum. [ABSTRACT FROM AUTHOR]
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- 2023
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7. Urinary Iodine Concentrations Indicate Iodine Deficiency in Pregnant Thai Women but Iodine Sufficiency in Their School-Aged Children.
- Author
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Gowachirapant, Sueppong, Winichagoon, Pattanee, Wyss, Laura, Tong, Bennan, Baumgartner, Jeannine, Melse-Boonstra, Alida, and Zimmermann, Michael B.
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IODINE ,PREGNANT women ,THAI women ,SCHOOL children ,PREGNANCY - Abstract
The median urinary iodine concentration (UI) in school-aged children is recommended for assessment of iodine nutrition in populations. If the median UI is adequate in school-aged children, it is usually assumed iodine intakes are also adequate in the remaining population, including pregnant women. But iodine requirements sharply increase during pregnancy. In this study, our aim was to measure UI in pairs of pregnant women and their school-aged children from the same family, who were sharing meals, to directly assess whether a household food basket that supplies adequate iodine to school-aged children also meets the needs of pregnant women. UI was measured in spot urine samples from pairs (n = 302) of healthy pregnant mothers and their school-aged children in metropolitan Bangkok, Thailand. A dietary questionnaire was completed. The UI (median (range)] in the pregnant women {108111-558) μg/L [0.85(0.086-4.41) μmoI/L]} were lower than those of their school-aged children {200(25-835) μg/L [1.58 (0.20-6.52) μmoI/L]} (P < 0.0011, indicating optimal iodine status in the children but mild-to-moderate iodine deficiency in their pregnant mothers. The estimated iodine intakes in the 2 groups were in the range of 130-170 μg/d. There was a modest positive correlation between UI in the pairs (r= 0.253; P < 0.01). A higher frequency of seafood meals was a significant predictor of UI in both groups, but household use of iodized salt was not. These data suggest the median UI in school-aged children should not be used as a surrogate for monitoring iodine status in pregnancy in central Thailand; pregnant women should be directly monitored. [ABSTRACT FROM AUTHOR]
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- 2009
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8. A Priori and a Posteriori Dietary Patterns among Pregnant Women in Johannesburg, South Africa: The NuPED Study.
- Author
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Conradie, Cornelia, Baumgartner, Jeannine, Malan, Linda, Symington, Elizabeth A., Cockeran, Marike, Smuts, Cornelius M., Faber, Mieke, and Féart, Catherine
- Abstract
Dietary pattern analyses allow assessment of the diet as a whole. Limited studies include both a priori and a posteriori dietary pattern analyses. This study aimed to explore the diet of pregnant women in urban South Africa through both a priori and a posteriori dietary pattern analyses and associated maternal and household factors. Dietary data were collected during early pregnancy using a quantified food frequency questionnaire from 250 pregnant women enrolled in the Nutrition During Pregnancy and Early Development (NuPED) cohort. A priori dietary patterns were determined using the Diet Quality Index-International (DQI-I), and a posteriori nutrient patterns using exploratory factor analysis. Based on the DQI-I, the study population followed a borderline low-quality diet. Three a posteriori nutrient patterns were identified: Pattern 1 "plant protein, iron, thiamine, and folic acid"; pattern 2 "animal protein, copper, vitamin A, and vitamin B
12 "; pattern 3 "fatty acids and sodium". Pattern 1 was associated with higher dietary quality (p < 0.001), lower maternal educational level (p = 0.03) and socioeconomic status (p < 0.001). Pattern 3 was significantly associated with lower dietary quality. The low dietary quality among pregnant women residing in urban South Africa should be addressed to ensure optimal maternal and offspring health outcomes. [ABSTRACT FROM AUTHOR]- Published
- 2021
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9. Associations of dietary patterns during pregnancy with perinatal fatigue and depression among urban women in South Africa : the NuPED study
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Smith, Vincent, Baumgartner, Jeannine, Conradie, Cornelia, 24054909 - Baumgartner, Jeannine (Supervisor), and 25872273 - Conradie, Cornelia (Supervisor)
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Pregnancy ,Perinatal fatigue ,Antenatal ,Perinatal depression ,Dietary patterns ,Nutrient patterns - Abstract
MSc (Dietetics), North-West University, Potchefstroom Campus Background: Perinatal depression is a serious problem worldwide and the prevalence is higher in low- and middle-income countries (LMIC) than in high-income countries (HIC). The South African prevalence of perinatal depression is estimated to be four times the global average. One of the potential risk factors for depression is an unhealthy diet, which women from LMIC have a higher risk of developing than women from HIC. An “unhealthier” diet has been associated with higher depressive symptoms during the perinatal period. Perinatal fatigue is common and has also been shown to have a bi-directional relationship with depression. Objectives: The aim of this study was to investigate the association between dietary patterns during early pregnancy and perinatal depression and fatigue among women. Methods: Forming part of the Nutrition during Pregnancy and Early Development (NuPED) study, dietary data were obtained at enrolment (< 18 weeks gestation) using a quantified food frequency questionnaire from which nutrient patterns were determined by means of exploratory factor analysis. The Edinburgh Postnatal Depression Scale (EPDS) was used to assess depressive symptoms and the Multidimensional Assessment of Fatigue (MAF) scale to measure fatigue at three time points during pregnancy and two postnatally. Results: The prevalence of perinatal depression ranged from 17.3% to 26.4% and perinatal fatigue ranged from 8.4% to 18.8% across the various time points. Three nutrient patterns were identified: 1) “Plant protein, iron, thiamine and folate”, which decreased the risk of fatigue at 6 months postnatally. This decrease in risk was attributed to the B-vitamins, iron and zinc present in the nutrient pattern; 2) “Animal protein, vitamin A, vitamin B12 and copper”, which increased the risk of depression at 12 months postnatally. The increased risk of depression may be due to the high meat content of the nutrient pattern; 3) “Fatty acids and sodium” which increased the risk for depression at 6 months postnatally. A possible reason for this increased risk of depression may be the high amount of saturated fatty acids in the nutrient pattern. Perinatal fatigue was also found to be positively associated with perinatal depression. Conclusion: This research illustrates the potential role of maternal diet during pregnancy in the development of maternal fatigue and depression. Masters
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- 2021
10. Associations between maternal dietary patterns during pregnancy and early childhood development in Johannesburg, South Africa
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Conradie, C., Smuts, C.M., Baumgartner, J., Faber, W.M., 20924445 - Smuts, Cornelius Mattheus (Supervisor), 24054909 - Baumgartner, Jeannine (Supervisor), and 21880972 - Faber, Willemina Maria (Supervisor)
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infant growth ,nutrition ,infant neurodevelopment ,pregnancy ,Dietary patterns ,fetal growth - Abstract
PhD (Nutrition), North-West University, Potchefstroom Campus Background and rationale. Pregnancy presents a unique period during which the health and well-being of the offspring can be influenced. Maternal nutrition is known as an important modifiable factor for both fetal and infant growth and development. Dietary pattern analysis allows for the assessment of the diet as a whole. The use of nutrients as variables for dietary pattern analysis rather than foods or food groups are advised as it is universal in consumption and allows for easier comparison between study populations. Studies investigating the associations of maternal dietary patterns during pregnancy with fetal and infant growth and development are limited, with most studies conducted in high-income countries. The aim of this study was therefore to assess the associations of maternal dietary patterns during pregnancy with fetal and infant growth and development up to the age of 12 months in Johannesburg, South Africa. Study design and methodology. Generally, healthy women pregnant with a singleton
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- 2021
11. Breast milk and erythrocyte fatty acid composition of lactating women residing in a peri‑urban South African township
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Linda Malan, Jennifer Ngounda, Cornelius M. Smuts, Tsitsi Chimhashu, Sicelosethu S. Siro, Jeannine Baumgartner, Adriaan Jacobs, Linda P. Siziba, 24095982 - Siziba, Liqhwa Patience, 13062778 - Jacobs, Adriaan, 10091130 - Malan, Linda, 20924445 - Smuts, Cornelius Mattheus, 24054909 - Baumgartner, Jeannine, and 25250930 - Chimhashu, Tsitsi
- Subjects
Adult ,Male ,0301 basic medicine ,Erythrocytes ,Breast milk ,Adolescent ,Urban Population ,Black african ,Clinical Biochemistry ,Peri ,030209 endocrinology & metabolism ,South Africa ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Animal science ,Pregnancy ,Humans ,Lactation ,Medicine ,Fatty acids ,Global Nutrition ,chemistry.chemical_classification ,Wereldvoeding ,030109 nutrition & dietetics ,Milk, Human ,business.industry ,Fatty Acids ,Infant ,food and beverages ,Fatty acid ,Mean age ,Cell Biology ,chemistry ,Female ,Composition (visual arts) ,Fatty acid composition ,business ,Lactating mothers ,Polyunsaturated fatty acid ,Maternal fatty acid status - Abstract
Data on breast milk fatty acid (FA) composition in South African lactating women in relation to their FA status, as well as on potential compositional changes within feed, are limited. The aim of this study was to assess the FA composition of breast milk sampled at three time points within feed, and to determine associations with red blood cell (RBC) total phospholipid FA levels in lactating South African mothers of 2–4-month-old breastfed infants. FA composition (% total FAs) was analyzed in RBC total phospholipids, and in fore-, mid-feed and hind-milk samples of lactating mothers (n = 100) of Black African descent living in a peri‑urban township. The mean age of the lactating women was 27.8 ± 6.8 years. Geometric mean (95% CI) breast milk SFA, MUFA and PUFA contents were 37.7 (37.3,38.1), 28.5 (27.9, 28.8), and 23.5 (23.2, 24.5)%, respectively. Breast milk DHA and AA contents were 0.25 (0.24, 3.71) and 0.81 (0.79, 0.83)%, respectively, in fore-, mid- and hind-milk combined. Maternal RBC EPA, DHA and AA levels were 0.37 (0.34, 0.40), 3.8 (3.6, 4.0) and 15.4 (14.8, 16.1)%, respectively. Women who reported to consume fish often (n = 3) had significantly higher RBC EPA levels than women who consumed fish sometimes (n = 56), never (n = 14) or rarely (n = 19). Breast milk DHA positively correlated with maternal RBC DHA, while no correlations were found between breast milk AA and maternal RBC AA. Breast milk ALA and DHA contents were significantly higher in mid-feed [ALA= 0.8 (0.2, 0.2), DHA=0.3 (0.2, 0.3)] and hind-milk [ALA=0.8 (0.8, 0.9), DHA=0.3 (0.3, 0.3)] than foremilk [ALA=0.8 (0.7, 0.9), DHA=0.2 (0.2, 0.3)]. In contrast, LA and AA contents remained constant within feed. In this sample of peri‑urban South African lactating mothers, breast milk was low in DHA and high in AA compared to global means. Breast milk DHA was associated with maternal RBC status, while breast milk AA was not. We further showed that breast milk ALA and DHA increased, while LA and AA remained unchanged within feed. This suggests that n-3 PUFA maybe preferentially transferred to breast milk within feed through biomagnification.
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- 2020
12. Maternal iron-deficiency is associated with premature birth and higher birth weight despite routine antenatal iron supplementation in an urban South African setting: the NuPED prospective study
- Author
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Linda Malan, Lizelle Zandberg, Elizabeth A. Symington, Cornelius M. Smuts, Cristian Ricci, Jeannine Baumgartner, Amy Wise, 24054909 - Baumgartner, Jeannine, 10091130 - Malan, Linda, 29790514 - Ricci, Cristian, 20924445 - Smuts, Cornelius Mattheus, 12135445 - Symington, Elizabeth A., and 12257656 - Zandberg, Lizelle
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Male ,0301 basic medicine ,Urban Population ,Physiology ,Maternal Health ,Pathology and Laboratory Medicine ,Biochemistry ,Hemoglobins ,South Africa ,0302 clinical medicine ,Pregnancy ,Prevalence ,Medicine and Health Sciences ,Birth Weight ,Prospective Studies ,030212 general & internal medicine ,Immune Response ,Multidisciplinary ,Anemia, Iron-Deficiency ,Obstetrics ,Nutritional Deficiencies ,Pregnancy Outcome ,Obstetrics and Gynecology ,Gestational age ,Anemia ,Hematology ,Iron deficiency ,Physiological Parameters ,Premature birth ,Premature Birth ,Gestation ,Medicine ,Female ,Research Article ,Adult ,medicine.medical_specialty ,Iron ,Birth weight ,Science ,Immunology ,Gestational Age ,Preterm Birth ,Young Adult ,03 medical and health sciences ,Signs and Symptoms ,Diagnostic Medicine ,Receptors, Transferrin ,medicine ,Humans ,Iron Deficiency Anemia ,Nutrition ,Inflammation ,Ferritin ,030109 nutrition & dietetics ,business.industry ,Pregnancy Complications, Hematologic ,Body Weight ,Infant, Newborn ,Biology and Life Sciences ,Proteins ,Protein Complexes ,medicine.disease ,Pregnancy Complications ,Iron-deficiency anemia ,Ferritins ,Iron Deficiency ,Birth ,Women's Health ,business - Abstract
Background Recent studies are suggesting a U-shaped relationship between antenatal iron exposure and birth outcomes. Little is known about the iron status and associated birth outcomes of pregnant women in South Africa. Our aim was to assess iron status at early, mid- and late pregnancy, and to determine associations with gestational age and birth weight in women in Johannesburg, South Africa. Methods In this prospective study of 250 pregnant women, we measured haemoglobin, biomarkers of iron status and inflammation at, PLoS ONE, 14 (9), ISSN:1932-6203
- Published
- 2019
13. Intake and status of iron and fatty acids during pregnancy in association with birth outcomes in women residing in urban South Africa
- Author
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Symington, Elizabeth Anna, Smuts, Cornelius Mattheus, and Baumgartner, Jeannine
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Pregnancy ,Birth weight ,Iron ,Anaemia ,Fatty acids ,Premature birth - Abstract
PhD (Nutrition), North-West University, Potchefstroom Campus, 2019. Nutrient requirements increase during pregnancy and women are vulnerable to inadequate nutritional status during this period of rapid foetal growth. Poor dietary intake and nutritional status during pregnancy have been associated with poor birth outcomes and increased risks for noncommunicable diseases in the offspring’s adult life. Low birth weight (LBW) and prematurity are risk factors for disease in later life. It would therefore benefit population health to identify and address predictors of LBW and preterm birth, particularly in low- and middle-income populations. In South Africa, approximately 15% of babies are born LBW and approximately 12% are born preterm. Maternal iron deficiency (ID) has been associated with increased risk for LBW, while poor omega-3 (n-3) polyunsaturated fatty acid (PUFA) intake and status have been associated with premature birth. Iron is important for erythropoiesis, growth and neurodevelopment. PUFAs form an important part of the structural component of cell membranes and play a critical role in cell signalling and are therefore considered essential for optimal foetal growth and development. There are limited data available on the diet as well as the nutritional status of pregnant women in South Africa. A national study on non-pregnant women of child-bearing age has indicated that 15% of women were ID and between 23% and 33% of women were anaemic. No national data exists for fatty acid status, however regional studies on non-pregnant women have indicated that fatty acid status were reflective of dietary intake and that n-3 PUFA intakes are low and n-6 PUFA high. It is probable that the South African iron and PUFA status may contribute to complications during pregnancy, specifically related to length of gestation and birth weight. Therefore, the aim of this research was to assess dietary intake and status of iron and long-chain polyunsaturated fatty acids (LCPUFA) during pregnancy; and to determine associations of maternal iron and LCPUFA status during pregnancy with birth outcomes, in particular gestational age and birth weight, in pregnant women giving birth at Rahima Moosa Mother and Child Hospital (RMMCH) in Johannesburg. A prospective, longitudinal study design was applied. Generally healthy pregnant women (5 mg/L) at enrolment. Multivariable regression analyses showed that anaemia and ID at 22 weeks, as well as IDE at 36 weeks of gestation were associated with higher birth weight (β=168.1; 95% CI: 19.5, 316.7 and β=227.6; 95% CI: 58.4, 396.8 and β=168.7; 95% CI: 27.9, 309.5, respectively). Women in the lowest ferritin quartile at 22 weeks gave birth to babies weighing 312 g (95% CI: 94.8, 528.8) more than those in the highest quartile. In contrast, IDE at 22 weeks was associated with a higher risk for premature birth (OR: 4.62, 95% CI: 1.56, 13.68) and women in lower haemoglobin quartiles at
- Published
- 2019
14. Nutrition during pregnancy and early development (NuPED) in urban South Africa: a study protocol for a prospective cohort
- Author
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Linda Malan, Elizabeth A. Symington, Lizelle Zandberg, Cristian Ricci, Jeannine Baumgartner, Cornelius M. Smuts, 24054909 - Baumgartner, Jeannine, 10091130 - Malan, Linda, 12257656 - Zandberg, Lizelle, 29790514 - Ricci, Cristian, 20924445 - Smuts, Cornelius Mattheus, and 12135445 - Symington, Elizabeth A.
- Subjects
Adult ,0301 basic medicine ,medicine.medical_specialty ,Urban Population ,Offspring ,Reproductive medicine ,Nutritional Status ,Early development ,lcsh:Gynecology and obstetrics ,Cohort Studies ,Eating ,South Africa ,Study Protocol ,03 medical and health sciences ,Child Development ,0302 clinical medicine ,Quality of life ,Pregnancy ,Environmental health ,Humans ,Birth outcomes ,Medicine ,Maternal diet ,030212 general & internal medicine ,Early childhood ,Prospective cohort study ,Prenatal Nutritional Physiological Phenomena ,lcsh:RG1-991 ,Nutrition ,030109 nutrition & dietetics ,business.industry ,DOHaD ,Infant, Newborn ,Obstetrics and Gynecology ,Prenatal Care ,medicine.disease ,Gestational diabetes ,Research Design ,Female ,Maternal health ,business ,Cohort study - Abstract
Background Adequate nutrition during pregnancy is important to ensure optimal birth outcomes, maternal health and offspring development. However, little is known about the dietary intake and nutritional status of pregnant women residing in urban South Africa. Therefore, the Nutrition during Pregnancy and Early Development (NuPED) cohort study was initiated to assess early nutrition-related exposures predictive of early childhood development in urban South Africa. Methods The aims of this prospective cohort study are: 1) to assess dietary intake and nutritional status of urban pregnant women in Johannesburg, South Africa, and 2) to determine associations with birth outcomes, measures of maternal health, as well as measures of offspring health and development. Pregnant women (
- Published
- 2018
15. How will South Africa’s mandatory salt reduction policy affect its salt iodisation programme? A cross-sectional analysis from the WHO-SAGE Wave 2 Salt & Tobacco study
- Author
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Jeannine Baumgartner, Lisa J. Ware, Aletta E. Schutte, Nirmala Naidoo, Karen E Charlton, Paul Kowal, Marike Cockeran, 10922180 - Schutte, Aletta Elisabeth, 24398330 - Ware, Lisa Jayne, 24054909 - Baumgartner, Jeannine, and 21102007 - Cockeran, Marike
- Subjects
Adult ,0301 basic medicine ,nutritional requirements ,Cross-sectional study ,Sodium ,Population ,Nutritional Status ,chemistry.chemical_element ,legislation ,Iodine ,Nutrition Policy ,Excretion ,South Africa ,03 medical and health sciences ,0302 clinical medicine ,Pregnancy ,Environmental health ,medicine ,Humans ,Longitudinal Studies ,030212 general & internal medicine ,Sodium Chloride, Dietary ,Salt intake ,education ,sodium ,Aged ,2. Zero hunger ,education.field_of_study ,030109 nutrition & dietetics ,iodine ,business.industry ,Research ,food ,General Medicine ,Middle Aged ,medicine.disease ,Iodine deficiency ,Cross-Sectional Studies ,chemistry ,Food, Fortified ,dietary ,Female ,Public Health ,business ,policy ,Cohort study - Abstract
ObjectiveThe WHO’s global targets for non-communicable disease reduction recommend consumption ofDesign/setting/participantsA nested cohort design within WHO’s 2015 Study on global AGEing and adult health (n=2887) including individuals from households across South Africa. Randomly selected adults (n=875) provided 24-hour and spot urine samples for sodium and iodine concentration analysis (the primary and secondary outcome measures, respectively). Median 24-hour urinary iodine excretion (UIE) and spot urinary iodine concentrations (UIC) were compared by salt intakes of 9 g/day.ResultsMedian daily sodium excretion was equivalent to 6.3 g salt/day (range 1–43 g/day); 35% had urinary sodium excretion values within the desirable range (9 g salt/day). Median UIC was 130 µg/L (IQR=58–202), indicating population iodine sufficiency (≥100 µg/L). Both UIC and UIE differed across salt intake categories (pConclusionsIn a nationally representative sample of South African adults, the association between indicators of population iodine status (UIC and UIE) and salt intake, estimated using 24-hour urinary sodium excretion, indicate that low salt intakes may compromise adequacy of iodine intakes in a country with mandatory iodisation of table salt. The iodine status of populations undergoing salt reduction strategies needs to be closely monitored to prevent re-emergence of iodine deficiency.
- Published
- 2018
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