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Objective: To investigate the clinical characteristics of pregnancy with pneumonia. Methods: A retrospective review of all admissions from January 1,2005 to December 30,2013 included 23 women who had been hospitalized with pneumonia during pregnancy in our hospital. 23 cases were divided into three groups according the first trimester, the second trimester and the third trimester. Data of clinical manifestations, laboratory examinations, treatment and prognosis of these patients were obtained and studied. Results: The incidence of respiratory system disease during pregnancy was 3.652%,pneumonia accounted for 0.965%,the incidence of community-acquired pneumonia (CAP) was 78.3% (18/23), hospital-acquired pneumonia (HAP) was 21.7% (5/23). 2 cases (8.7%) were in the first trimester, 10 cases (43.5%) were in the second trimester, and 11 cases (47.8%) were in the third trimester. It suggested that the incidence of pregnancy with pneumonia accompanied with the trimester. The incidences of cough, fever, and shortness of breath and expectoration were 82.6% (19/23), .2% (15/23), 60.9% (14/23) and 43.5% (10/23), and shortness of breath is particularly evident in the third trimester, the difference was statistically significant (P<0.05), but cough, expectoration, chills, fever and other symptoms has no significant differences in different trimesters (P>0.05), the differences of blood count and biochemistry index were not statistically different in the different trimesters (P>0.05). On the other hand, cases with anemia was 43.5%(10/23), which was one of the risk factors of pregnant with pneumonia. The incidence of spontaneous abortion and premature delivery were 8.7% (2/23), and mature delivery were 82.6% (19/23),and no neonatal death. Conclusions: Pneumonia may be more severe in the pregnant woman, and carries significant risk to both mother and fetus. The incidence of CAP in the third trimester is higher than in the first and second trimester, and the clinical manifestations were similar with nonpregnant women, but has higher asthma incidence in the third trimester with pneumonia. Anemia is one of the risk factors of pregnancy complicated with pneumonia. [ABSTRACT FROM AUTHOR]

Thrombotic thrombocytopenic purpura (TTP) is a rare life-threatening disorder. It is characterized by microan-giopathic hemolytic anemia, progressive thrombocytopenia, central nervous system disorder, fever and acute renal failure. It is caused by the absent or severe deficiency of the von Willebrand factor-cleaving protease named ADAMTS13. The pathogenesis of TTP is unknown, usually triggered after pregnancy. It causes maternal morbidity and fetal loss. Prompt aggressive management should include timely termination of pregnancy, plasma transfusion and/or plasma exchange. [ABSTRACT FROM AUTHOR]