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To reveal the typical features of text duplication in papers from four medical fields: basic medicine, health management, pharmacology and pharmacy, and public health and preventive medicine. To analyze the reasons for duplication and provide suggestions for the management of medical academic misconduct. In total, 2,469 representative Chinese journal papers were included in our research, which were submitted by researchers in 2020 and 2021. A plagiarism check was carried out using the Academic Misconduct Literature Check System (AMLC). We generated a corrected similarity index based on the AMLC general similarity index for further analysis. We compared the similarity indices of papers in four medical fields and revealed their trends over time; differences in similarity index between review and research articles were also analyzed according to the different fields. Further analysis of 143 papers suspected of plagiarism was also performed from the perspective of sections containing duplication and according to the field of research. Papers in the field of pharmacology and pharmacy had the highest similarity index (8.67 ± 5.92%), which was significantly higher than that in other fields, except health management. The similarity index of review articles (9.77 ± 10.28%) was significantly higher than that of research articles (7.41 ± 6.26%). In total, 143 papers were suspected of plagiarism (5.80%) with similarity indices ≥ 15%; most were papers on health management (78, 54.55%), followed by public health and preventive medicine (38, 26.58%); 90.21% of the 143 papers had duplication in multiple sections, while only 9.79% had duplication in a single section. The distribution of sections with duplication varied among different fields; papers in pharmacology and pharmacy were more likely to have duplication in the data/methods and introduction/background sections, however, papers in health management were more likely to contain duplication in the introduction/background or results/discussion sections. Different structures for papers in different fields may have caused these differences. There were three limitations to our research. Firstly, we observed that a small number of papers have been checked early. It is unknown who conducted the plagiarism check as this can be included in other evaluations, such as applications for Science and technology projects or awards. If the authors carried out the check, text with high similarity indices may have been excluded before submission, meaning the similarity index in our research may have been lower than the original value. Secondly, there were only four medical fields included in our research. Additional analysis on a wider scale is required in the future. Thirdly, only a general similarity index was calculated in our study; other similarity indices were not tested. A comprehensive analysis of similarity indices in four medical fields was performed. We made several recommendations for the supervision of medical academic misconduct and the formation of criteria for defining suspected plagiarism for medical papers, as well as for the improved accuracy of text duplication checks. We quantified the differences between the AMLC general similarity index and the corrected index, described the situation around text duplication and plagiarism in papers from four medical fields, and revealed differences in similarity indices between different article types. We also revealed differences in the sections containing duplication for papers with suspected plagiarism among different fields. [ABSTRACT FROM AUTHOR]

Despite progress in the prevention and diagnosis of cancer, current technologies for tumor detection present several limitations including invasiveness, toxicity, inaccuracy, lengthy testing duration and high cost. Therefore, innovative diagnostic techniques that integrate knowledge from biology, oncology, medicinal and analytical chemistry are now quickly emerging in the attempt to address these issues. Following this approach, here we developed a paper-based electrochemical device for detecting cancer-derived Small Extracellular Vesicles (S-EVs) in fluids. S-EVs were obtained from cancer cell lines known to express, at a different level, the αvβ6 integrin receptor, a well-established hallmark of numerous epithelial cancer types. The resulting biosensor turned out to recognize αvβ6-containing S-EVs down to a limit of 0.7*103 S-EVs/mL with a linear range up to 105 S-EVs /mL, and a relative standard deviation of 11%, thus it may represent a novel opportunity for αvβ6 expressing cancers detection. The detection of cancer in its early stages can greatly prevent disease development, however, current technologies for tumor detection present several limitations. Here, the authors develop a paper-based electrochemical device for detecting cancer-derived small extracellular vesicles (S-EVs) in fluids, recognizing αvβ6-containing S-EVs down to a limit of 0.7*103 S-EVs/mL with a linear range up to 105 S-EVs/mL. [ABSTRACT FROM AUTHOR]

The article outlines the intricate process of applying nutrition evidence to personalized care, emphasizing the importance of sound evidence-based dietary advice in maintaining health and managing diseases. It also discusses the challenges faced in integrating research findings into individualized nutrition interventions, including navigating conflicting information sources and tailoring treatments to diverse health and social situations.

Introduction: Over the last decade, the emergence and spread of personalized medicine (PM) have defined a substantial revolution in healthcare. In principle, healthcare system sustainability is challenged by the investments required for research and development, as well as the adoption of PM techniques in routine clinical care. The "Integrating China in the International Consortium for Personalized Medicine" (IC2PerMed) EU-funded project aims to integrate China into the "International Consortium for Personalized Medicine" (ICPerMed). IC2PerMed aims to align the EU and China's research agendas in this field to enable a swift development of approaches in the EU and China with strong leverage upon EU-Chinese collaborations. Methods: Within this project, we first mapped relevant policies on PM in both the EU and China, and then we involved European and Chinese experts in PM in workshops and Delphi surveys in order to identify relevant priorities for the implementation of PM in sustainable healthcare. Results: As a result of this process, we identified nine overarching priorities, each addressing specific aspects of the sustainability of healthcare systems and PM implementation, with the main goal of supporting policymakers in integrating PM approaches in the EU and China. Discussion/conclusion: The implementation of PM in health systems is appealing in terms of improved accuracy in diagnostics, treatment, and prevention of disease, as well as reduction of the side effects resulting from inefficient use of drugs. Research, development, and implementation of needed techniques require time and resources that can slow the adoption of PM in healthcare systems. The nine priorities we identified address some of the most critical points, trying to lay the foundations for a comprehensive approach. [ABSTRACT FROM AUTHOR]

Objective: We have reported that implementation of an electronic health record (EHR) based quality improvement system that included point-of-care electronic reminders accelerated improvement in performance for multiple measures of chronic disease care and preventive care during a 1-year period. This study examined whether providing pre-visit paper quality reminders could further improve performance, especially for physicians whose performance had not improved much during the first year., Design: Time-series analysis at a large internal medicine practice using a commercial EHR. All patients eligible for each measure were included (range approximately 100-7500)., Measurements: The proportion of eligible patients in the practice who satisfied each of 15 quality measures after removing those with exceptions from the denominator. To analyze changes in performance for individual physicians, two composite measures were used: prescribing seven essential medications and completion of five preventive services., Results: During the year after implementing pre-encounter reminders, performance continued to improve for eight measures, remained stable for four, and declined for three. Physicians with the worst performance at the start of the pre-encounter reminders showed little absolute improvement over the next year, and most remained below the median performance for physicians in the practice., Conclusions: Paper pre-encounter reminders did not appear to improve performance beyond electronic point-of-care reminders in the EHR alone. Lagging performance is likely not due to providers' EHR workflow alone, and trying to step backwards and use paper reminders in addition to point-of-care reminders in the EHR may not be an effective strategy for engaging slow adopters.

Objectives: This study evaluated knowledge structure and its effect factor by analysis of co-author and keyword networks in Korea's preventive medicine sector., Methods: The data was extracted from 873 papers listed in the Journal of Preventive Medicine and Public Health, and was transformed into a co-author and keyword matrix where the existence of a 'link' was judged by impact factors calculated by the weight value of the role and rate of author participation. Research achievement was dependent upon the author's status and networking index, as analyzed by neighborhood degree, multidimensional scaling, correspondence analysis, and multiple regression., Results: Co-author networks developed as randomness network in the center of a few high-productivity researchers. In particular, closeness centrality was more developed than degree centrality. Also, power law distribution was discovered in impact factor and research productivity by college affiliation. In multiple regression, the effect of the author's role was significant in both the impact factor calculated by the participatory rate and the number of listed articles. However, the number of listed articles varied by sex., Conclusions: This study shows that the small world phenomenon exists in co-author and keyword networks in a journal, as in citation networks. However, the differentiation of knowledge structure in the field of preventive medicine was relatively restricted by specialization.

The nurse is the main link for the patient's adaptation to his health condition. Based on observations, actions and clarifications from the former, the latter can understand what affects their health status, adopt practices or manage the new condition, and even perform self-care. The role modeling theory developed by Helen Erickson, Evelyn Tomlin and Mary Swain portrays the nurse-patient interaction and caring as an instrument for adapting to the health situation. With the objective of knowing the scientific production that applies it in women's health care. An integrative review study was carried out on productions published between 1998 and 2016, in international journals, in English, Spanish and Portuguese, using the VHL Nursing, PubMed and Scopus platforms. Among the articles found, four were selected for analysis that addressed women's health care and the use of theory. It was observed the flexibility of adoption of the same in studies of assistance to the health of the parturient, of the chemical dependent, in addition to the prevention of diseases to the women's health. The usefulness of paper modeling and its potential for teaching and research promoting self-efficacy in women's health can be seen. [ABSTRACT FROM AUTHOR]

Objectives: The present review aims to summarize the state‐of‐the‐art von Willebrand disease (VWD) treatment focusing on specific clinical settings (obstetrics, surgery, long‐term prophylaxis and comorbidities) as well as on the use of a Von Willebrand factor (VWF) concentrate with low FVIII content. Methods: Literature research and case reports. Results and Conclusions: Considering that patients affected by VWD have an intact ability to synthesize FVIII, in order to avoid excessive levels of FVIII, a highly purified plasma VWF concentrate with low FVIII content could be particularly useful in those patients and clinical circumstances at high thrombotic risk as well as for long‐term prophylaxis. When deciding the optimal therapeutic strategy, physicians should take into account both the patient's history and the differences among available concentrates according to the clinical situations requiring treatment. [ABSTRACT FROM AUTHOR]

The emerging field of genomic medicine offers an opportunity for biology and anatomy teachers to bring the topics of DNA, genetics, molecular processes, and evolution together into one experience. Through the genomic medicine paradigm, students see the unbroken connection between small biological topics such as mutations and their potential connection to disease phenotypes. In this paper, we present as a main example cystic fibrosis, which is an often-studied genetic disease in general biology class, for examination through the genomic medicine lens. Concepts such as genes, the plasma membrane, variation, mutations, the nucleus, and chromosomes can be used in a narrative and visual approach to genetics through the genomic medicine standpoint to engage and connect students with next-generation genomics and with the fundamental unit of life -- the cell. It is through the genomic medicine lens that the cell's context and relationship to the evolving world takes place.

The research aimed to develop a paper box with 10–300 μl of cardamom oil to improve rambutan storage, reduce waste, and explore reuse possibilities. The experiment investigated the delay in mold growth caused by the post-harvest disease, Pestalotiopsis sp., both on the medium and on rambutan fruit under storage conditions of 10 ± 2 °C and approximately 80% RH. The results showed that CM at 300 μl significantly inhibited Pestalotiopsis sp. mycelium and spore germination on the medium, while a lower volume of 30 μl effectively delayed mold incidence on rambutan during the 14-day storage period. The confirmed antifungal mode of action indicated that CM disrupted Pestalotiopsis sp. ergosterol and cell membrane integrity, resulting in mycelium lysis and damaged morphology, thereby inhibiting its growth. The active fruit box can be reused for at least 2 or 3 storage cycles, effectively delaying rambutan decay and preserving its color change parameters. By using the box with 30 μl of CM, rambutan's shelf-life was extended to 14 days compared to the control's shelf-life of around 7 days. Active paper boxes offer a valuable solution for improving post-harvest fruit storage and transportation, benefiting both farmers and consumers. • A paper box with a CM paper pad effectively delayed the growth of Pestalotiopsis sp. • CM vapor released from packaging damaged the conidia and mycelium of Pestalotiopsis sp. • The paper box with CM can be reused at least twice to preserve the quality of rambutans. • CM showed destructive potential in the cell membrane of the fungi. • CM could maintain the quality of rambutan during storage seven to 14 days of storage. [ABSTRACT FROM AUTHOR]

This paper presents an analysis of the socio-scientific dimensions which 46 11th graders, enrolled in the subject scientific culture, consider to justify their COVID-19 vaccination decision and how they managed to combine and integrate these dimensions before and after working on a sequence of activities aimed at learning about argumentation in science. Although almost all the students intended to be vaccinated against COVID-19, the results show that before the sequence, they used one or two dimensions to justify their decision, while after it, some combined up to five dimensions. The ethical and social-cultural dimensions were two of the most frequently used. The scientific dimension was infrequent in the initial argument but was, however, the most used dimension in the final argument, after the intervention. Working on socioscientific issues encourages the development of argumentation skills, and, in this specific case, health education skills as well.

This article presented the World Health Organization’s (WHO) recommendations on the use of Rabies vaccines excerpted from the Rabies vaccines: WHO position paper – April 2018 published in the Weekly Epidemiological Record [1] This position paper replaces the 2010 WHO position paper on rabies vaccines [2] . It presents new evidence in the field of rabies and the use of rabies vaccines, focussing on programmatic feasibility, simplification of vaccination schedules and improved cost-effectiveness. The recommendations concern the 2 main immunization strategies, namely vaccination for post-exposure prophylaxis and vaccination for pre-exposure prophylaxis. In the context of post-exposure prophylaxis, recommendations are also provided on the use of rabies immunoglobulins. Footnotes to this paper provide a number of core references including references to grading tables that assess the quality of the scientific evidence, and to the evidence-to-recommendation tables. In accordance with its mandate to provide guidance to Member States on health policy matters, WHO issues a series of regularly updated position papers on vaccines and combinations of vaccines against diseases that have an international public health impact. These papers are concerned primarily with the use of vaccines in large-scale immunization programmes; they summarize essential background information on diseases and vaccines, and conclude with WHO’s current position on the use of vaccines in the global context. Recommendations on the use of cholera vaccines were discussed by the Strategic Advisory Group of Experts (SAGE) in October 2017; evidence presented at these meetings can be accessed at: http://www.who.int/immunization/sage/meetings/2017/october/presentations_background_docs/en/ . [ABSTRACT FROM AUTHOR]

Personalized Medicine is a challenge for healthcare systems in Central and Eastern Europe if they are to provide patients with personalized diagnosis and treatment. Personalized medicine (PM) is about tailoring a treatment as individualized as the disease. [1] Integrated care involves receiving care along a continuum of health promotion, disease prevention, diagnosis, treatment, disease-management, rehabilitation and palliative care services, coordinated across the different levels and sites of care within and beyond the health sector, and according to the needs of patients throughout the life course. Personalized Medicine and Integrated Care are among the most important concepts related to the management and organization of healthcare systems. This article intends to identify challenges to the adoption of personalized medicine and stimulate fruitful dialogue and debate about the evaluation of barriers and facilitators within the implementation of personalized medicine interventions, identify the barriers and take systematic actions to remove as many of them as possible to create a future where PM is fully integrated into real-life settings. [ABSTRACT FROM AUTHOR]

This study sought to identify the opinions of the Egyptian academic medical elite in the treatment of news sites for preventive medicine crises (corona vaccine model) and their assessment of this treatment and their trends towards it. The study relied on the method of media survey and it used the tool of electronic and paper questionnaire to collect data. The Egyptian academic medical elite chose the site of the seventh day with a relative weight of (61) in the front of the sites that were keen to follow it in the treatment of the Corona vaccine, and then sky news Arabic at a relative weight (57), and then the website BBC Arabic at a relative weight (56), and also chose breaking news form first, which is keen to follow it in the treatment of corona vaccine at a relative weight of (80.3), and then live broadcast at a relative weight (62), and then news reports at a relative weight (61). (48.5%) of respondents considered corona vaccine treatment on news sites to be fairly in-depth, (37.9%) felt superficial, and (13.6%) felt it was in-depth. A statistically significant correlation between the assessment of the Egyptian academic medical elite to address corona vaccine news sites and the degree of follow-up to them has been established. A statistically significant correlation between the degree of follow-up of the Egyptian academic medical elite to treat corona vaccine on news sites and their levels of confidence has also been established, while a statistically significant correlation between the elite's follow-up score for corona vaccine treatment on news sites and the effects of follow-up has not been established. [ABSTRACT FROM AUTHOR]