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Start Over Author "Rosso, S.M." Topic prions
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1. Tau negative frontal lobe dementia at 17q21: significant finemapping of the candidate region to a 4.8 cM interval.

Author

Rademakers, R., Cruts, M., Dermaut, B., Sleegers, K., Rosso, S.M., Van de Broeck, M., Backhovens, H., van Swieten, J., van Duijn, C.M., and Van Broeckhoven, C.

Subjects
GENOMES, DEMENTIA, ALZHEIMER'S disease, PRIONS, EXONS (Genetics)
Abstract

Presents the results of a genome-wide search in a four-generation pedigree with autosomal dominant early-onset dementia. Exclusion of the known Alzheimer's disease genes and mutations in the prion protein gene and exons 9-13 of the microtubule; Resemblance of the phenotype to frontotemporal dementia.

Published
2002
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