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The experiment was to study the effect of Fuzi Lizhong decoction plus or minus compound Chinese medicine preparation on production performance and blood physical and chemical indexes of fertile sows. A total of 96 'Landrace× Large' binary hybrid sows with reproductive disorders were selected, and randomly divided into four groups, with four replicates in each group and six pigs in each replicate. Pigs in group A, group B and group C were fed with 3%, 2% and 1% Fuzi Lizhong decoction plus or minus compound Chinese medicine preparation in basic diet, and pigs in group D (control group) pigs were fed with 0.5% antibiotic in basic diet. The test period was 150 d. The results showed that the average litter size of group B was significantly higher than that of control group (P<0.05). The average number of live piglets in three Chinese medicine groups were significantly increased (P<0.05), the average birth weight and daily weight gain of piglets were extremely increased (P<0.01), and the average number of mummified fetuses and the diarrhea rate of piglets were significantly decreased (P<0.05). Before medication, all other blood indexes except MONO and GRAN were abnormal. After medication, the HGB and HCT of pigs in each group returned to normal values. The WBC of pigs in three traditional Chinese medicine groups returned to the normal value, while control group was still abnormal. The RBC of pigs in group A and group B returned to normal values, while those in group C and control group were abnormal. The MCHC of pigs in group A returned to normal, while the control group was still abnormal. Before medication, except serum ALB, A/G and UREA, other blood biochemical indexes of pigs in each group were in abnormal range. After medication, the blood ALT and GLU of pigs in three test groups returned to normal values, while control group remained at abnormal levels. The study indicates that the compound Chinese medicine preparation can effectively increase the number of sows born and live, reduce the number of dead and mummified fetuses, increase the average birth weight, uniformity, daily weight gain of piglets, and reduce the diarrhea rate of piglets. Combined with comprehensive analysis and evaluation of cost, the recommended addition amount was still abnormal. Before medication, except serum ALB, A/G and UREA, other blood biochemical indexes of pigs in each group were in abnormal range. After medication, the blood ALT and GLU of pigs in three test groups returned to normal values, while control group remained at abnormal levels. The study indicates that the compound Chinese medicine preparation can effectively increase the number of sows born and live, reduce the number of dead and mummified fetuses, increase the average birth weight, uniformity, daily weight gain of piglets, and reduce the diarrhea rate of piglets. Combined with comprehensive analysis and evaluation of cost, the recommended addition amount is 2%. [ABSTRACT FROM AUTHOR]