2 results on '"Oggioni, Roberto"'
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2. Pentraxin 3 in patients with severe sepsis or shock: the ALBIOS trial
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Caironi, Pietro, Masson, Serge, Mauri, Tommaso, Bottazzi, Barbara, Leone, Roberto, Magnoli, Michela, Barlera, Simona, Mamprin, Filippo, Fedele, Andrea, Mantovani, Alberto, Tognoni, Gianni, Pesenti, Antonio, Gattinoni, Luciano, Latini, Roberto, Bruzzone, Paola, Pagan, Francesca, Russo, Riccarda, Confalonieri, Andrea, Abbruzzese, Chiara, Vergnano, Beatrice, Faenza, Stefano, Siniscalchi, Antonio, Pierucci, Elisabetta, Noto, Andrea, Pezzi, Angelo, Spanu, Paolo, Parrini, Vieri, Oggioni, Roberto, Pasetti, Giovanni Stefano, Casadio, Maria Cinzia, Buontempo, Rosa, Carrer, Sara, Piccoli, Francesca, Rizzi, Tatiana, Caricato, Anselmo, La Sala, Monica, Antonaci, Alessandra, Fassini, Paola, Paganini, Silvia, Porta, Virginia, Moise, Gabriella, Marell, Silvia, Furia, Mirella, Urbano, Maria Cristina, Carobbi, Roberta, Poleni, Simona, Kandil, Hassan, Ballotta, Andrea, Bettini, Fabrizio, Sanseverino, Manlio, Gatta, Alessandro, Cecchini, Francesca, Guatteri, Luca, Ciceri, Gabriella, Raimondi, Ferdinando, Colombo, Roberto, Ferraris, Sandra, Borelli, Massimo, Bellato, Valentina, Cancellieri, Franco, Senni, Silvia, Bertocchi, Ester, Ferri, Paola, Moioli, Gianpietro, Molin, Alexandra, Salati, Giovanni, Salsi, Pierpaolo, Brunori, Emanuela, Elisei, Daniele, Maggio, Giuseppe, Nicola, Federico Guardia, Cavana, Marco, Morelli, Giacomo, Guarino, Arturo, Isetta, Michele, Tulli, Giorgio, Mangani, Valerio, Rossi, Nicola, Ferrari, Marta, Bona, Francesco, Vay, Monica, Bartoli, Teresa, Gallo, Mauro, Vettoretto, Katiuscia, Della Morte, Mauro, Boselli, Enrico, Puscio, Daniela, Bovo, Monia, Galzerano, Antonio, Carli, Manuela, Zagara, Giovanni, Caironi, Pietro, Masson, Serge, Mauri, Tommaso, Bottazzi, Barbara, Leone, Roberto, Magnoli, Michela, Barlera, Simona, Mamprin, Filippo, Fedele, Andrea, Mantovani, Alberto, Tognoni, Gianni, Pesenti, Antonio, Gattinoni, Luciano, Latini, Roberto, Bruzzone, Paola, Pagan, Francesca, Russo, Riccarda, Confalonieri, Andrea, Abbruzzese, Chiara, Vergnano, Beatrice, Faenza, Stefano, Siniscalchi, Antonio, Pierucci, Elisabetta, Noto, Andrea, Pezzi, Angelo, Spanu, Paolo, Parrini, Vieri, Oggioni, Roberto, Pasetti, Giovanni Stefano, Casadio, Maria Cinzia, Buontempo, Rosa, Carrer, Sara, Piccoli, Francesca, Rizzi, Tatiana, Caricato, Anselmo, La Sala, Monica, Antonaci, Alessandra, Fassini, Paola, Paganini, Silvia, Porta, Virginia, Moise, Gabriella, Marell, Silvia, Furia, Mirella, Urbano, Maria Cristina, Carobbi, Roberta, Poleni, Simona, Kandil, Hassan, Ballotta, Andrea, Bettini, Fabrizio, Sanseverino, Manlio, Gatta, Alessandro, Cecchini, Francesca, Guatteri, Luca, Ciceri, Gabriella, Raimondi, Ferdinando, Colombo, Roberto, Ferraris, Sandra, Borelli, Massimo, Bellato, Valentina, Cancellieri, Franco, Senni, Silvia, Bertocchi, Ester, Ferri, Paola, Moioli, Gianpietro, Molin, Alexandra, Salati, Giovanni, Salsi, Pierpaolo, Brunori, Emanuela, Elisei, Daniele, Maggio, Giuseppe, Nicola, Federico Guardia, Cavana, Marco, Morelli, Giacomo, Guarino, Arturo, Isetta, Michele, Tulli, Giorgio, Mangani, Valerio, Rossi, Nicola, Ferrari, Marta, Bona, Francesco, Vay, Monica, Bartoli, Teresa, Gallo, Mauro, Vettoretto, Katiuscia, Della Morte, Mauro, Boselli, Enrico, Puscio, Daniela, Bovo, Monia, Galzerano, Antonio, Carli, Manuela, and Zagara, Giovanni
- Subjects
0301 basic medicine ,Male ,Resuscitation ,Clinical Biochemistry ,030204 cardiovascular system & hematology ,albumin ,pentraxin 3 ,prognosis ,septic shock ,severe sepsis ,Gastroenterology ,Severity of Illness Index ,Biochemistry ,0302 clinical medicine ,Albumin ,Aged ,Albumins ,Biomarkers ,C-Reactive Protein ,Crystalloid Solutions ,Female ,Fluid Therapy ,Humans ,Isotonic Solutions ,Italy ,Linear Models ,Middle Aged ,Mortality ,Multiple Organ Failure ,Multivariate Analysis ,Prognosis ,Randomized Controlled Trials as Topic ,Sepsis ,Serum Amyloid P-Component ,Shock, Septic ,biology ,Medicine (all) ,Shock ,General Medicine ,PTX3 ,3. Good health ,Shock (circulatory) ,Cohort ,medicine.symptom ,prognosi ,medicine.medical_specialty ,Article ,03 medical and health sciences ,Internal medicine ,Severity of illness ,Settore MED/41 - ANESTESIOLOGIA ,medicine ,Septic shock ,business.industry ,Septic ,C-reactive protein ,medicine.disease ,Surgery ,030104 developmental biology ,biology.protein ,business ,severe sepsi - Abstract
Background The long pentraxin PTX3 is a key component of the humoral arm of innate immunity related to sepsis severity and mortality. We evaluated the clinical and prognostic significance of circulating PTX3 in the largest cohort ever reported of patients with severe sepsis or septic shock. Design Plasma PTX3 was measured on days 1, 2 and 7 after randomization of 958 patients to albumin or crystalloids for fluid resuscitation in the multicenter Albumin Italian Outcome Sepsis (ALBIOS) trial. We tested the association of PTX3 and its changes over time with clinical severity, prevalent and incident organ dysfunctions, 90-day mortality, and treatment. Results PTX3 was high at baseline (72 [33-186] ng/mL) and rose with the severity and number of organ dysfunctions (p
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- 2017
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