1. Characteristics of peripheral white blood cells in COVID-19 patients revealed by a retrospective cohort study
- Author
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Xunliang Tong, Anqi Cheng, Xueting Yuan, Xuefeng Zhong, He Wang, Wei Zhou, Xiaomao Xu, and Yanming Li
- Subjects
COVID-19 ,Lymphocytes ,Eosinophils ,Prognosis ,Immune response ,Infectious and parasitic diseases ,RC109-216 - Abstract
Abstract Background Peripheral hematological changes in severe COVID-19 patients may reflect the immune response during SARS-CoV-2 infection. Characteristics of peripheral white blood cells as early signals were needed to be investigated for clarifying its associations with the fatal outcomes in COVID-19 patients. Methods A retrospective cohort study was performed and the hospitalized COVID-19 patients were recruited in wards of Sino-French New City Branch of Tongji Hospital in Wuhan, Hubei province, China. Characteristics of peripheral white blood cells in survivors and non-survivors were analyzed. Comparison among patients with different level of eosinophils was performed. Results Of 198 patients included in this study, 185 were discharged and 13 died. Levels of eosinophils, lymphocytes and basophils in non-survivors were significantly lower than those in survivors. Death rate in low eosinophils group was higher and no patient died in normal eosinophils group (16.7% vs 0, P
- Published
- 2021
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