1. Treating silent reflux disease does not improve poorly controlled asthma.
- Author
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Riscili BP, Parsons JP, and Mastronarde JG
- Subjects
- Adolescent, Adult, Asthma complications, Esophageal pH Monitoring, Female, Gastroesophageal Reflux complications, Humans, Male, Multicenter Studies as Topic statistics & numerical data, Omeprazole therapeutic use, Treatment Outcome, Young Adult, Anti-Ulcer Agents therapeutic use, Asthma prevention & control, Gastroesophageal Reflux drug therapy, Practice Guidelines as Topic standards, Proton Pump Inhibitors therapeutic use, Randomized Controlled Trials as Topic statistics & numerical data
- Abstract
Many patients with asthma also have gastroesophageal reflux disease (GERD), and GERD can cause symptoms that mimic those of poorly controlled asthma. Patients with poorly controlled asthma are often treated empirically for GERD, whether or not they have symptomatic reflux. However, a randomized, placebo-controlled trial funded by the American Lung Association and the National Institutes of Health found that treating silent GERD does not improve asthma control. These results warrant a reevaluation of current guidelines and clinical practice.
- Published
- 2010
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