1. Synthesis and.
- Author
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Elgogary, Sameh Ramadan, Hashem, Neveen Mohamed, and Khodeir, Mohamed Nabeel
- Subjects
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POLYPHOSPHORIC acid , *METHYL ethyl ketone , *CHLOROFORM , *HETEROCYCLIC compounds , *HETEROCYCLIC chemistry - Abstract
Synthesis of linear and angular furocoumarins with new skeleton structure of potential photobiological feature interest was carried out through Williamson reaction of hydroxycoumarins with 3-chloro-2-butanone followed by with polyphosphoric acid or by heating in a strongly alkaline solution. The reactions of synthesized furocoumarins were performed in chloroform and in the presence of tetraphenylporphyrin as singlet oxygen sensitizer (1O2). The reactions afforded the photocleaved product through [2 + 2] and the photooxygenated products through and [4 + 2] . The photoproducts were isolated and fully characterized by spectral analyses. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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