6 results on '"Li Shen"'
Search Results
2. Geospatial characteristics of measles transmission in China during 2005−2014.
- Author
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Yang, Wan, Wen, Liang, Li, Shen-Long, Chen, Kai, Zhang, Wen-Yi, and Shaman, Jeffrey
- Subjects
MEASLES ,VIRAL vaccines ,GEOSPATIAL data ,VACCINATION of children ,PUBLIC health ,INFECTIOUS disease transmission - Abstract
Measles is a highly contagious and severe disease. Despite mass vaccination, it remains a leading cause of death in children in developing regions, killing 114,900 globally in 2014. In 2006, China committed to eliminating measles by 2012; to this end, the country enhanced its mandatory vaccination programs and achieved vaccination rates reported above 95% by 2008. However, in spite of these efforts, during the last 3 years (2013–2015) China documented 27,695, 52,656, and 42,874 confirmed measles cases. How measles manages to spread in China—the world’s largest population—in the mass vaccination era remains poorly understood. To address this conundrum and provide insights for future public health efforts, we analyze the geospatial pattern of measles transmission across China during 2005–2014. We map measles incidence and incidence rates for each of the 344 cities in mainland China, identify the key socioeconomic and demographic features associated with high disease burden, and identify transmission clusters based on the synchrony of outbreak cycles. Using hierarchical cluster analysis, we identify 21 epidemic clusters, of which 12 were cross-regional. The cross-regional clusters included more underdeveloped cities with large numbers of emigrants than would be expected by chance (p = 0.011; bootstrap sampling), indicating that cities in these clusters were likely linked by internal worker migration in response to uneven economic development. In contrast, cities in regional clusters were more likely to have high rates of minorities and high natural growth rates than would be expected by chance (p = 0.074; bootstrap sampling). Our findings suggest that multiple highly connected foci of measles transmission coexist in China and that migrant workers likely facilitate the transmission of measles across regions. This complex connection renders eradication of measles challenging in China despite its high overall vaccination coverage. Future immunization programs should therefore target these transmission foci simultaneously. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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3. Spatiotemporal Clustering Analysis and Risk Assessments of Human Cutaneous Anthrax in China, 2005–2012.
- Author
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Zhang, Wen-Yi, Wang, Li-Ya, Zhang, Xiu-Shan, Han, Zhi-Hai, Hu, Wen-Biao, Qian, Quan, Haque, Ubydul, Soares Magalhaes, Ricardo J., Li, Shen-Long, Tong, Shi-Lu, Li, Cheng-Yi, Sun, Hai-Long, and Sun, Yan-Song
- Subjects
ANTHRAX ,PUBLIC health ,EPIDEMICS ,DISEASE incidence ,CLUSTER analysis (Statistics) ,DISEASE risk factors - Abstract
Objective: To investigate the epidemic characteristics of human cutaneous anthrax (CA) in China, detect the spatiotemporal clusters at the county level for preemptive public health interventions, and evaluate the differences in the epidemiological characteristics within and outside clusters. Methods: CA cases reported during 2005–2012 from the national surveillance system were evaluated at the county level using space-time scan statistic. Comparative analysis of the epidemic characteristics within and outside identified clusters was performed using using the χ
2 test or Kruskal-Wallis test. Results: The group of 30–39 years had the highest incidence of CA, and the fatality rate increased with age, with persons ≥70 years showing a fatality rate of 4.04%. Seasonality analysis showed that most of CA cases occurred between May/June and September/October of each year. The primary spatiotemporal cluster contained 19 counties from June 2006 to May 2010, and it was mainly located straddling the borders of Sichuan, Gansu, and Qinghai provinces. In these high-risk areas, CA cases were predominantly found among younger, local, males, shepherds, who were living on agriculture and stockbreeding and characterized with high morbidity, low mortality and a shorter period from illness onset to diagnosis. Conclusion: CA was geographically and persistently clustered in the Southwestern China during 2005–2012, with notable differences in the epidemic characteristics within and outside spatiotemporal clusters; this demonstrates the necessity for CA interventions such as enhanced surveillance, health education, mandatory and standard decontamination or disinfection procedures to be geographically targeted to the areas identified in this study. [ABSTRACT FROM AUTHOR]- Published
- 2015
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4. Scrub Typhus in Mainland China, 2006–2012: The Need for Targeted Public Health Interventions.
- Author
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Zhang, Wen-Yi, Wang, Li-Ya, Ding, Fan, Hu, Wen-Biao, Soares Magalhaes, Ricardo J., Sun, Hai-Long, Liu, Yun-Xi, Liu, Qi-Yong, Huang, Liu-Yu, Clements, Archie C. A., Li, Shen-Long, and Li, Cheng-Yi
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TSUTSUGAMUSHI disease ,PUBLIC health ,BACTERIAL diseases - Abstract
This article provides an overview of a study on the incidence and distribution of scrub typhus in mainland China from 2006 to 2012. Scrub typhus is a bacterial infection transmitted by chigger mites, primarily found in areas where infected rodents are present. The study found a total of 27,391 confirmed cases of scrub typhus during the study period, with a higher incidence among females in 2011 and 2012. The disease was most prevalent among individuals aged 60-69 and farmers had a higher incidence compared to non-farmers. The study emphasizes the need for targeted public health interventions to control and prevent scrub typhus outbreaks in China. [Extracted from the article]
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- 2013
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5. Spatiotemporal Patterns of Japanese Encephalitis in China, 2002–2010.
- Author
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Wang, Li-Ya, Zhang, Wen-Yi, Ding, Fan, Hu, Wen-Biao, Soares Magalhaes, Ricardo J., Sun, Hai-Long, Li, Yi-Xing, Zou, Wen, Wang, Yong, Liu, Qi-Yong, Li, Shen-Long, Yin, Wen-Wu, Huang, Liu-Yu, Clements, Archie C. A., Bi, Peng, and Li, Cheng-Yi
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JAPANESE B encephalitis ,SPATIOTEMPORAL processes ,ENCEPHALITIS ,MULTIVARIATE analysis ,PUBLIC health ,DISEASE risk factors - Abstract
Objective: The aim of the study is to examine the spatiotemporal pattern of Japanese Encephalitis (JE) in mainland China during 2002–2010. Specific objectives of the study were to quantify the temporal variation in incidence of JE cases, to determine if clustering of JE cases exists, to detect high risk spatiotemporal clusters of JE cases and to provide evidence-based preventive suggestions to relevant stakeholders. Methods: Monthly JE cases at the county level in mainland China during 2002–2010 were obtained from the China Information System for Diseases Control and Prevention (CISDCP). For the purpose of the analysis, JE case counts for nine years were aggregated into four temporal periods (2002; 2003–2005; 2006; and 2007–2010). Local Indicators of Spatial Association and spatial scan statistics were performed to detect and evaluate local high risk space-time clusters. Results: JE incidence showed a decreasing trend from 2002 to 2005 but peaked in 2006, then fluctuated over the study period. Spatial cluster analysis detected high value clusters, mainly located in Southwestern China. Similarly, we identified a primary spatiotemporal cluster of JE in Southwestern China between July and August, with the geographical range of JE transmission increasing over the past years. Conclusion: JE in China is geographically clustered and its spatial extent dynamically changed during the last nine years in mainland China. This indicates that risk factors for JE infection are likely to be spatially heterogeneous. The results may assist national and local health authorities in the development/refinement of a better preventive strategy and increase the effectiveness of public health interventions against JE transmission. [ABSTRACT FROM AUTHOR]
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- 2013
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6. The first human infection with severe fever with thrombocytopenia syndrome virus in Shaanxi Province, China.
- Author
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Wei, Jing, Li, Shen, Dong, Jian-Hua, Tian, Hui, Chowell, Gerardo, Tian, Huai-Yu, Lv, Wen, Han, Zong-Qi, Xu, Bing, Yu, Peng-Bo, and Wang, Jing-Jun
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THROMBOCYTOPENIA , *EMERGING infectious diseases , *SEROPREVALENCE , *BLOOD serum analysis , *ENZYME-linked immunosorbent assay , *AGE groups , *PUBLIC health - Abstract
Summary Background Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease discovered in China in 2009. In July 2013, the first human infection with SFTS virus (SFTSV) was detected in Shaanxi Province, Western China. Methods A seroprevalence study among humans was carried out in an SFTS endemic village; specifically, serum samples were collected from 363 farmers in an SFTS endemic village in Shaanxi Province. The presence of SFTSV antibodies in serum was determined using an ELISA. Results SFTSV antibodies were found in a total of 20 people (5.51%), with no significant difference between males and females (6.93% and 4.42%, respectively; Chi-square = 1.29, p = 0.25). Moreover, the SFTSV antibody positive rate was not significantly different across different age groups (Chi-square = 2.23, p = 0.69). Conclusions SFTSV readily infects humans with outdoor exposure. The results of the serological study indicate that the virus circulates widely in Shaanxi Province. SFTSV represents a public health threat in China. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
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