1. Mindfulness-based cognitive therapy in COPD: a cluster randomised controlled trial.
- Author
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Farver-Vestergaard I, O'Toole MS, O'Connor M, Løkke A, Bendstrup E, Basdeo SA, Cox DJ, Dunne PJ, Ruggeri K, Early F, and Zachariae R
- Subjects
- Adaptation, Psychological, Aged, Denmark, Female, Humans, Linear Models, Male, Middle Aged, Psychiatric Status Rating Scales, Pulmonary Disease, Chronic Obstructive physiopathology, Quality of Life, Severity of Illness Index, Surveys and Questionnaires, Treatment Outcome, Cognitive Behavioral Therapy methods, Mindfulness, Pulmonary Disease, Chronic Obstructive psychology, Pulmonary Disease, Chronic Obstructive therapy
- Abstract
A considerable proportion of patients with chronic obstructive pulmonary disease (COPD) entering pulmonary rehabilitation (PR) report psychological distress, which is often accompanied by poor physical health status. Mindfulness-based cognitive therapy (MBCT) has been shown to improve psychological and physical outcomes in other chronic diseases. We therefore evaluated the efficacy of MBCT as an add-on to a standard PR programme in COPD.COPD patients eligible for PR were cluster randomised to receive either an 8-week, group-based MBCT programme as an add-on to an 8-week PR programme (n=39), or PR alone (n=45). The primary outcomes of psychological distress and physical health status impairment were measured with the Hospital Anxiety and Depression Scale (HADS) and the COPD Assessment Test (CAT) before randomisation (T1), mid- (T2) and post-intervention (T3), and at 3 (T4) and 6 (T5) months' follow-up .A statistically significant time×arm effect was found for the HADS (Cohen's d =0.62, 95% CIs ( d )=0.18-1.06, p=0.010). The treatment effect on the CAT failed to reach statistical significance ( d =0.42, 95% CIs ( d )=-0.06-0.90, p=0.061).MBCT showed a statistically significant and durable effect on psychological distress, indicating that MBCT may be an efficacious add-on to standard PR programmes in COPD., Competing Interests: Conflict of interest: Disclosures can be found alongside this article at erj.ersjournals.com, (Copyright ©ERS 2018.)
- Published
- 2018
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