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A new one-pot four component procedure for synthesis of densely functionalized pyrroles using commercially available ninhydrin with phosphorane intermediates produced in the reaction between triphenylphosphine, ammonium thiocyanate (or ammonium acetate) and various dialkyl acetylenedicarboxylates was developed.

Tetrahydroindeno [1,2-b]pyrrole-3-carboxylate were synthesized in a one-pot procedure by the reaction of 1,3-dicarbonyl and activated carbonyl compounds such as benzyl or ninhydrin in ethanol/water in the presence of ammonium acetate. J. Heterocyclic Chem., (2011). [ABSTRACT FROM AUTHOR]

A mild and efficient synthesis of highly substituted pyrroles using the reaction of triphenylphosphine, α-diketone, ammonium acetate, and dialkyl acetylenedicarboxylates is described. [ABSTRACT FROM AUTHOR]

Facile reaction involving 4-hydroxy proline and activated carbonyl compounds such as 11H-indeno[1,2-b]quinoxalin-11- one and isatin derivatives catalyzed by silica sulfuric acid under microwave irradiation yielding some novel 11-(1H-pyrrol-1-yl)-11Hindeno[ 1,2-b]quinoxaline and 3-(1H-pyrrol-1-yl)indolin-2-one derivatives are described. [ABSTRACT FROM AUTHOR]

Abstract: 11H-Indeno[1,2-b]quinoxalin-11-ones generated in situ from ninhydrin and various 1,2-phenylenediamines, catalysed by montmorillonite K10 under microwave irradiation, condense with 4-hydroxyproline to produce 11-(1H-pyrrol-1-yl)-11H-indeno[1,2-b]quinoxaline derivatives in good yields. [Copyright &y& Elsevier]

11-(1H-Pyrrol-1-yl)-11H-indeno[1,2-b]quinoxaline and 3-(1Hpyrrol-1-yl)indolin-2-one derivatives have been synthesized in good yields in a novel, one-pot, and efficient process by condensation of 11H-indeno[1,2-b]quinoxalin-11-one or isatin derivatives with 4-hydroxyproline on solid-support montmorillonite K10 under microwave irradiation. [ABSTRACT FROM AUTHOR]