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Efficacy of ricobendazole in 10 % solution for injection against the most helminthosis of cattle are studied. Therapeutic dosis of ricobendazole (4 mg/kg) were determined. The drug was showed 98–100% efficacy against dictyocaulosis, gastrointestinal nematodosis, monieziosis. Fasciola hepatica, Trichocephalis ovis were more resistant to action of ricobendazole.

Test of Ricobendazole used for treatment of moniesiosis was conducted in the farm «Krasny Put» in Pestravsk district of Samara region in June-July 2013. 40 lambs sponta- neously infected with Moniesia spp. were selected for testing. By strongilatosis of the gastrointestinal tract Ricobendazole was tested in the same farm in June July 2013 on 26 wedders (gelded rams) in the age of 1-1,5 years spontaneously infected with various spe- cies of Strongylata. By dictyocaulosis and other lung strongilatosis Ricobendazole was tested on 24 spontaneously infected sheep selected after examination of feces according to Berman method. Efficacy of Ricobendazole against various species of Anoplocephala is studied in June-August 2013 in farms of Samara region that are unfavorable in relation to avitellinosis and tisaniesiosis in sheep spontaneously infected with Avitellinae centri- punctata (12 heads) and Thisaniezia giardi (10 heads). By trichocephalosis the medicine is tested on different groups of sheep at the dose of 4, 6 and 8 mg/kg. Anthelmintic effi- cacy of Ricobendazole is studied by main helminthosis in sheep. Ricobendazole at the dose of 4 mg/kg showed 100 % efficacy against Nematodirus spp. and other Strongylata of gastrointestinal tract, Dictyocaulus filaria, 99,9 % - against Moniezia spp., 85,8 % - against Mullerius capillaris, 84,7 % - against Protostrongylus spp., 96,1 % - against Аvitellina centripunctata, 99,2 % - against Th. giardi and 73,9 % - against T. ovis.

Efficacy of the injective anthelmintic drug Ritril produced on the base of Ricobendazole and Triclabendazole used in treatment of different types of helminthosis in cattle has been studied. It was determined that Ritril has a high anthelmintic efficacy when administered at a dose of 0,8 ml/10 kg of body weight. The drug shown a 100% efficacy in treatment of dictyocaulosis and strongylatosis of gastrointestinal tract. Fasciola spp. and Trichocephala spp. were more resistant to the effect of Ritril. Therefore it is recommended to use the drug at a higher dose – 1,6 ml/10 kg of body weight.