1. Transoral robotic surgery alone for oropharyngeal cancer: quality-of-life outcomes.
- Author
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Choby GW, Kim J, Ling DC, Abberbock S, Mandal R, Kim S, Ferris RL, and Duvvuri U
- Subjects
- Carcinoma, Squamous Cell mortality, Carcinoma, Squamous Cell pathology, Female, Follow-Up Studies, Humans, Male, Middle Aged, Natural Orifice Endoscopic Surgery psychology, Neoplasm Staging, Oropharyngeal Neoplasms mortality, Oropharyngeal Neoplasms pathology, Prospective Studies, Retrospective Studies, Surveys and Questionnaires, Survival Rate, Treatment Outcome, Carcinoma, Squamous Cell psychology, Carcinoma, Squamous Cell surgery, Natural Orifice Endoscopic Surgery methods, Oropharyngeal Neoplasms psychology, Oropharyngeal Neoplasms surgery, Quality of Life, Robotics
- Abstract
Importance: Few studies have examined quality-of-life (QOL) outcomes in patients who undergo transoral robotic surgery (TORS) alone (ie, without adjuvant radiotherapy or chemoradiotherapy)., Objective: To report QOL outcomes of patients with oropharyngeal squamous cell carcinoma who receive only TORS., Design, Setting, and Participants: Medical records for all patients undergoing TORS for treatment of primary oropharyngeal squamous cell carcinoma from May 1, 2010, to March 31, 2014, at a tertiary care academic cancer center were examined from June through September 2014. Thirty-four patients who did not receive adjuvant therapy after TORS were included in the study., Intervention: Primary surgical resection via TORS., Main Outcomes and Measures: The University of Washington Quality of Life, version 4, questionnaire was completed by patients preoperatively and at 1-, 6-, 12-, and 24-month intervals after TORS. Demographic, clinicopathologic, and follow-up data were collected., Results: Mean follow-up time was 14 months (May 1, 2010, to April 30, 2014). Most patients had T1 (20 [59%]) or T2 (13 [38%]) and N0 (13 [38%]) or N1 (16 [47%]) disease. Statistically significant improvement in QOL outcomes was noted in the following postoperative domains: chewing from 1 month (median, 50 [IQR, 50-100]) to 12 months (100 [IQR, 100-100]; P = .048), swallowing from 1 month (70 [IQR, 30-85]) to 6 months (100 [IQR, 70-100]; P = .047) and 1 to 24 months (100 [IQR, 70-100]; P = .048), pain from 1 month (38 [IQR, 25-75]) to 6 months (88 [IQR, 75-100]; P = .006) and 1 to 12 months after surgery (100 [IQR, 75-100]; P = .01), and activity from 1 month (63 [IQR, 50-88]) to 24 months (100 [IQR, 75-100]; P = .03). Two participants (6%) died during the follow-up period: 1 because of disease and 1 because of a myocardial infarction. Two patients (6%) required temporary gastrostomy tube placement, but none required tracheostomy., Conclusions and Relevance: Appropriately selected patients who undergo TORS alone for oropharyngeal squamous cell carcinoma experience acceptable short- and long-term QOL outcomes.
- Published
- 2015
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