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The rapid development of vaccines to combat the spread of COVID-19 disease caused by the SARS-CoV-2 virus is a great scientific achievement. Before the development of the COVID-19 vaccines, most studies capitalized on the available data that did not include pharmaceutical measures. Such studies focused on the impact of non-pharmaceutical measures (e.g social distancing, sanitation, wearing of face masks, and lockdown) to study the spread of COVID-19. In this study, we used the SIDARTHE-V model which is an extension of the SIDARTHE model wherein we include vaccination roll outs. We studied the impact of vaccination on the severity (deadly nature) of the virus in African countries. Model parameters were extracted by fitting simultaneously the COVID-19 cumulative data of deaths, recoveries, active cases, and full vaccinations reported by the governments of Ghana, Kenya, Mozambique, Nigeria, South Africa, Togo, and Zambia. With countries having some degree of variation in their vaccination programs, we considered the impact of vaccination campaigns on the death rates in these countries. The study showed that the cumulative death rates declined drastically with the increased extent of vaccination in each country; while infection rates were sometimes increasing with the arrival of new waves, the death rates did not increase as we saw before vaccination., Comment: 40 pages, 10 figures

We studied the COVID-19 pandemic evolution in selected African countries. For each country considered, we modeled simultaneously the data of the active, recovered and death cases. In this study, we used a year of data since the first cases were reported. We estimated the time-dependent basic reproduction numbers, $R_0$, and the fractions of infected but unaffected populations, to offer insights into containment and vaccine strategies in African countries. We found that $R_0\leq 4$ at the start of the pandemic but has since fallen to $R_0 \sim 1$. The unaffected fractions of the populations studied vary between $1-10$\% of the recovered cases., Comment: 27 pages, 9 figures and 1 table