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Aims To examine changes in health-related quality of life throughout the course of pregnancy and among three pairs of consecutive periods (pre-pregnancy to early pregnancy, early to middle pregnancy and middle to late pregnancy), as well as to identify associated obstetric factors during the entire period of pregnancy. Background Only sparse data are available concerning the profiles of health-related quality of life throughout pregnancy. Design A within-subject comparison was undertaken. Methods In total, 358 women completed the Taiwanese version of the Medical Outcomes Study Short Form-36 Health Questionnaire and a demographic-obstetric questionnaire at three stages of pregnancy at a medical centre. The participants were recruited between 2009-2010. A generalized estimating equation regression model was employed for the repeated measures. Results The scores for physical component summary decreased significantly throughout early, middle and late pregnancy. The scores for mental component summary increased. The scores for physical, mental component summary and the eight domains of health-related quality of life decreased significantly from pre-pregnancy to early pregnancy. After adjusting for demographic and clinical factors, significant factors predicting physical component summary during pregnancy included stage of pregnancy and previous infertility. The factors predicting mental component summary included stage of pregnancy, parity and medical condition. Conclusions The results revealed the dynamic pattern of perceived health status by the Taiwanese pregnant women in their surrounding socio-cultural context and identified the stage of pregnancy and obstetric factors predicting health-related quality of life. [ABSTRACT FROM AUTHOR]

Objective: To examine the correlation of function, quality of life (QOL), and parental impact on developmental delayed children. Methods: Sixty parents of children with developmental delays ( M: F = 36:24, mean age 4 years and 2 months) and 56 parents of age-sex matched typical development children were included. Pediatric Outcomes Data Collection Instrument and Child Health Questionnaire for children, World Health Organization-QOL, Impact on Family Scale, and Hospital Anxiety and Depression Scale for parents were assessed. Results: Functional performance was correlated with physical component of QOL in children (correlation coefficients: 0.7-0.9; p < 0.01), age of children (0.3-0.4; p < 0.05) and parents (0.3; p < 0.05), maternal employment (0.3-0.4; p < 0.05), parental QOL (0.3-0.4; p < 0.01), family impact (−0.3 to −0.5; p < 0.01), and parental emotion (−0.3 to −0.4; p < 0.05). Conclusions: Children who exhibited higher levels of function had higher QOL, as did their parents, and less parental impact. [ABSTRACT FROM AUTHOR]

Background The relationship between concurrent or previous postnatal pain and depressive symptoms remains controversial. To the best of our knowledge, no previous study has used validated measures and multiple scales to evaluate perineal pain, or examined its relationship with depressive symptoms during the postpartum period. Objectives We investigated the association between pain and previous postnatal pain with depression during the 6-month postpartum period, and the influence of previous postnatal depressive symptoms. Design A prospective cohort study design was used. Setting Maternity unit of a medical center. Participants This study included 432 participants; data regarding demographic characteristics, perineal pain, and any pain and depression during the 6-month postpartum period were collected. Methods Pain and depressive symptoms were measured using the Short Form-McGill Pain Questionnaire and Center for Epidemiologic Studies Depression Scale, respectively. A generalized estimating equation was used to examine factors associated with postpartum depression. Results After adjusting for covariates, women who had perineal pain at 4–6 weeks postpartum showed an increased risk for depression at 4–6 weeks (risk ratio [RR]: 1.9, 95% confidence limits [CL]: 1.2, 3.2) and 6 months (RR: 1.9, 95% CL: 1.1, 3.3) compared to those with no perineal pain. Perineal pain severity, 4–6 weeks postpartum, also predicted depressive symptoms at 6 months postpartum ( β = 0.63, p = 0.02). Any pain intensity score at 3–5 days postpartum predicted depression at 3 months ( β = 0.01, p = 0.04). Women with high depression scores at 3–5 days had a two- or three-fold higher risk for depression at 4–6 weeks and 3 and 6 months, respectively, compared to those with low depression scores (RR: 3.5, 95% CL: 2.2, 5.4; RR: 2.2, 95% CL: 1.3, 3.4; and RR: 2.8, 95% CL: 1.7, 4.8, respectively). Conclusions Our study provides robust evidence that perineal pain 4–6 weeks postpartum is associated with depressive symptoms 4–6 weeks and 6 months postpartum; pain at 3–5 days postpartum predicts depressive symptoms at 3 months postpartum; and previous postnatal depressive symptoms, particularly depressive symptoms 3–5 days postpartum, predict depressive symptoms during the 6-month postpartum period. [ABSTRACT FROM AUTHOR]