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AIM: To compare the ciliary body thickness between eyes with primary angle closure (PAC) and primary angle-closure glaucoma (PACG) with the normal eyes, and to investigate the association between ciliary body thickness and ciliary processes situation. METHODS: In this cross-sectional study, 57 patients with PAC/PACG were matched to 57 normal subjects after propensity score matching (PSM) adjusting for age and gender. All subjects underwent conventional ocular examinations and ultrasound biomicroscopy (UBM) examination, among which the patients with PAC/PACG performed the examinations one month after laser peripheral iridotomy (LPI). Quantitative parameters were measured, which included ciliary body thickness at the position of 1 mm posterior to the scleral spur (CBT1), trabecular-ciliary process distance (TCPD) and trabecular-ciliary process angle (TCA). RESULTS: Eyes with PAC/PACG presented significantly thinner CBT1, shorter TCPD and smaller TCA (P

AIM: To investigate the effect of Mingmu Yanggan Pills combined with sodium hyaluronate eye drops on the clinical efficacy of patients with dry eye(DE)in perimenopausal women and the influence on the levels of IL-33 and IL-6 in tears. METHODS: Eighty patients(160 eyes)with perimenopausal women with dry eye were enrolled in this study. They were randomly divided into observation group(n=40)and control group(n=40). The control group was given sodium hyaluronate eye drops. The observation group was given Mingyu yanggan Pill on the basis of the control group. The curative effect of the two groups were observed. The changes of ocular surface disease index(OSDI)score, tear film break-up time(BUT), tear secretion test(SⅠt)and corneal fluorescein staining(FL)and IL-33 and IL-6 levels in tears before and after treatment were compared. RESULTS: The total score of OSDI for the two groups after treatment were significantly lower than those before treatment(PPPPχ2=5.591, P=0.018). CONCLUSION: Mingmu Yanggan Pills combined with sodium hyaluronate eye drops has a good curative effect on the treatment of dry eye in perimenopausal women, which may be related to the decrease of IL-33 and IL-6 levels in tears.

AIM: To investigate the effect of Carbomer eye gel and recombinant human epidermal growth factor(rhEGF)on dry eye after cataract surgery in diabetics.METHODS:A total of 160 patients(160 eyes)with diabetes undergone phacoemulsification with a diagnosis of dry eyes were randomized divided into two groups, treatment group(80 cases, 80 eyes)and control group(80 cases, 80 eyes). In treatment group, the patients were treated by Carbomer eye gel and rhEGF. In control group, the patients were treated by Carbomer eye gel. The subjective dry eye symptoms, tear break-up time(BUT), Schirmer I test(SⅠt)and cornea fluorescein staining(FL)were observed before treatment, 1, 4wk after treatment.RESULTS: There was no significant difference between groups before treatment(P>0.05). After treatment at 1, 4wk, the subjective dry eye symptoms and the results of three examination(BUT, SⅠt and FL)in two groups better than those before treatment(PPPPCONCLUSION: Carbomer eye gel can relieve the dry eye symptoms of diabetes after phacoemulsification effectively, and it can be more effective to combine Carbomer eye gel with rhEGF at early stage after phacoemulsification.

AIM: To compare the different formulas in intraocular lens(IOL)power calculations on high myopia after LASIK with cataract patients who received the phacoemulsification and intraocular lens implantation(Phaco+IOL). METHODS: This was a retrospective study. Data from 102 eyes of 61 cataract patients with high myopia, who received Phaco+IOL after LASIK, were collected. Patients were divided into three groups by formulas in IOL power calculations before surgery: Holladay group(11 cases, 21 eyes), Haigis-L group(30 cases, 47 eyes)and SRK-T group(20 cases, 34 eyes). The ratios of equivalent IOL power after LASIK were predicted and the accuracy of their predictions were compared 3mo after surgery. It was an index of reliability of the formulas outcomes.RESULTS:The ratios of equivalent IOL power after LASIK using the Holladay, Haigis-L and SRK-T formulas were 0.86±0.41D, 0.43±0.30D and 1.27±0.58D, respectively. There was no significant difference between Holladay group and SRK-T group(t=-0.271, P=0.625>0.05). However, significant difference was found between Haigis-L group and Holladay group(t=2.249, P=0.047t=6.012, P=0.031CONCLUSION: The Haigis-L formula is more accurate than the SRK-T and Holladay formulas in predicting IOL power for cataract patients with high myopia after LASIK.