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Start Over Author "Takayama, Chihiro" Topic reactive oxygen species
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1. ROS-mediated synthetic growth defect caused by impaired metabolism of sphingolipids and phosphatidylserine in budding yeast.

Author

Toda T, Urita A, Koga A, Takayama C, and Tani M

Subjects
Phosphatidylserines metabolism, Reactive Oxygen Species metabolism, Saccharomycetales growth & development, Saccharomycetales metabolism, Sphingolipids metabolism
Abstract

Previously, we found that yeast exhibits a strong growth defect with the combination of a lack of gene involved in structural modification of sphingolipids and repression of the phosphatidylserine synthase gene. Here we found that the double gene mutation causes reactive oxygen species-mediated cell growth defect, which is suppressed by deletion of LEM3 encoding the subunit of phospholipid flippase.

Published
2020
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