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Your search keyword '"Chazot, P L"' showing total 7 results
Start Over Author "Chazot, P L" Topic receptors, histamine h3
7 results on '"Chazot, P L"'

2. Histamine H3 and H4 receptors are expressed on distinct endocrine cell types in the rat fundic mucosa.

Author

Morini G, Becchi G, Shenton FC, Chazot PL, and Grandi D

Subjects
Animals, Eating, Gastric Fundus metabolism, Gastric Mucosa metabolism, Male, Rats, Rats, Wistar, Receptors, Histamine H4, Gastric Fundus cytology, Gastric Mucosa cytology, Protein Isoforms metabolism, Receptors, G-Protein-Coupled metabolism, Receptors, Histamine metabolism, Receptors, Histamine H3 metabolism
Published
2008
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3. Probing the importance of N-glycosylation for [(3)H] clobenpropit binding to human H (3) receptors expressed in HEK 293 cells . 3. Molecular and chemical aspects of the histamine receptors.

Author

Shenton FC and Chazot PL

Subjects
Cell Line, Glycosylation, Humans, Kidney cytology, Protein Processing, Post-Translational, Receptors, Histamine H3 drug effects, Thiourea metabolism, Histamine Antagonists metabolism, Imidazoles metabolism, Receptors, Histamine H3 metabolism, Thiourea analogs & derivatives
Published
2006
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4. Evidence for native and cloned H3 histamine receptor higher oligomers.

Author

Shenton FC, Hann V, and Chazot PL

Subjects
Animals, Cell Line, Cross-Linking Reagents, Dimerization, Humans, Molecular Weight, Prosencephalon metabolism, Protein Binding, Protein Structure, Quaternary, Rats, Receptors, Histamine H3 genetics, Recombinant Proteins chemistry, Recombinant Proteins genetics, Recombinant Proteins metabolism, Receptors, Histamine H3 chemistry, Receptors, Histamine H3 metabolism
Published
2005
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6. Overview: H3 histamine receptor isoforms: new therapeutic targets in the CNS?

Author

Chazot PL and Hann V

Subjects
Animals, Attention Deficit Disorder with Hyperactivity drug therapy, Cognition Disorders drug therapy, Epilepsy drug therapy, Histamine Agonists therapeutic use, Humans, Huntington Disease drug therapy, Parkinson Disease drug therapy, Receptors, Histamine H3 drug effects, Receptors, Histamine H3 ultrastructure, Signal Transduction drug effects, Signal Transduction physiology, Central Nervous System drug effects, Central Nervous System Diseases drug therapy, Histamine Agonists pharmacology, Receptors, Histamine H3 chemistry
Published
2001

7. Immunological identification of the mammalian H3 histamine receptor in the mouse brain.

Author

Chazot PL, Hann V, Wilson C, Lees G, and Thompson CL

Subjects
Age Factors, Animals, Antibodies isolation & purification, Humans, Immunohistochemistry, Mice, Mice, Inbred Strains, Peptide Fragments immunology, Rabbits, Rats, Rats, Wistar, Antibody Specificity, Brain Chemistry, Receptors, Histamine H3 analysis, Receptors, Histamine H3 immunology
Abstract

Affinity-purified antibodies raised against the peptide sequence H3 (349-358) receptor specifically recognized two protein species with Mr 62,000 and 93,000 in adult mouse forebrain membranes. Both immunoreactive species were suppressed greatly by preincubation of the antibody with the respective peptide. Immunohistochemical analysis using affinity-purified anti-H3 (349-358) antibodies yielded a high degree of coincidence with ligand-autoradiographical information, with high levels detected in the CA3 and dentate gyrus of the hippocampus, laminae V of the cerebral cortex, the olfactory tubercle, Purkinje cell layer of the cerebellum, substantia nigra, globus pallidus, thalamus and striatum. This study suggests further biochemical evidence for multiple H3 receptor subtypes and the widespread distribution of the H3 receptor in the mammalian brain.

Published
2001
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