This paper presents unique data on the reproductive behavior of the rare giant armadillo (Priodontes maximus), including gestation, inter-birth intervals, number of offspring and parental care. It also describes a potential non-parental infanticide. The study used telemetry, camera traps and track observations for over 7 years in a 300-km2 area in the central Brazilian Pantanal. Females with young were recorded 5 times. Reproductive events did not appear to be seasonal. A 5-month gestation period was estimated. Parental care is long, as the offspring is completely dependent on its mother's milk until 6–8 months of age. Weaning was estimated to occur at 11–12 months, but the offspring continued to be dependent on its mother's burrows until 18 months old. Three births were recorded over a 6-year period for one individual. The offspring from the first birth recorded was killed at 4 weeks of age in a potential infanticide, but 7 months after the first birth, a second offspring was born. A third birth was recorded 3 years after the second birth. Results from this study suggest that the population growth rate of giant armadillos is very low and the species can therefore easily be locally extirpated. [ABSTRACT FROM AUTHOR]