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2 results on '"Xiao, Jian-Qi"'

1. Acupuncture for hearing loss after traumatic brain injury

Author

Wang, Wei-feng, Yang, Lin-hong, Yu, Hai-jiang, Zhang, Shu-hong, and Xiao, Jian-qi

Subjects
safety, Male, traumatic brain injury, Acupuncture Therapy, effectiveness, Treatment Outcome, Research Design, Study Protocol Systematic Review, randomized controlled trial, Brain Injuries, Traumatic, Humans, Female, Hearing Loss, acupuncture, Research Article, Randomized Controlled Trials as Topic, Systematic Reviews as Topic
Abstract

Background: This study aims to systematically assess the effectiveness and safety of acupuncture on hearing loss (HL) after traumatic brain injury (TBI). Methods: In this study, the following databases will be retrieved from inception up to the May 1, 2019: PUBMED, EMBASE, Cochrane Library, Cumulative Index to Nursing and Allied Health Literature, Allied and Complementary Medicine Database, and Chinese Biomedical Literature Database. All databases will be retrieved without any language restrictions. Two reviewers will independently carry out article selection, data collection, and risk of bias evaluation. Any disagreements will be solved by a third reviewer through discussion. Results: This study will systematically investigate the effectiveness and safety of acupuncture for treating HL after TBI through evaluating HL assessment, hearing threshold, quality of life, and adverse events. Conclusion: The expected findings of this study will provide latest evidence for assessing the effectiveness and safety of acupuncture for HL after TBI. Ethics and dissemination: This study is supposed to be published in a peer-reviewed journal. No ethical approval is needed because this study will based on the literature analysis, but not the individual patient. PROSPERO registration number: PROSPERO CRD42019133417.

Published
2019

2. Correlations of Pituitary Tumor Transforming Gene Expression with Human Pituitary Adenomas: A Meta-Analysis.

Author

Xiao, Jian-Qi, Liu, Xiao-Hai, Hou, Bo, Yao, Yong, Deng, Kan, Feng, Min, Xing, Bin, Lian, Wei, Wang, Ren-Zhi, and Feng, Feng

Subjects
*PITUITARY tumors, *GENE expression, *GENETIC transformation, *GROWTH factors, *PARACRINE mechanisms, *NEOVASCULARIZATION, *MEDICAL databases
Abstract

Objective: Pituitary tumor transforming gene (PTTG) is an important paracrine growth factor involved in early lactotrope transformation and early onset of angiogenesis in pituitary hyperplasia. Emerging evidences have shown that PTTG expression may contribute to the etiology of pituitary adenomas; but individually published studies showed inconclusive results. This meta-analysis aimed to derive a more precise estimation of the correlations of PTTG expression with human pituitary adenomas. Methods: A range of electronic databases were searched: MEDLINE (1966∼2013), the Cochrane Library Database (Issue 12, 2013), EMBASE (1980∼2013), CINAHL (1982∼2013), Web of Science (1945∼2013) and the Chinese Biomedical Database (CBM) (1982∼2013) without language restrictions. Meta-analysis was performed using the STATA 12.0 software. Crude odds ratio (OR) or standard mean difference (SMD) with its corresponding 95% confidence interval (95%CI) were calculated. Results: Twenty-four clinical cohort studies were included with a total of 1,464 pituitary adenomas patients. The meta-analysis results revealed that patients with invasive pituitary adenomas had higher positive expression of PTTG than those of non-invasive patients (OR  = 6.68, 95%CI  = 3.72–11.99, P<0.001). We also found a significant difference in microvessel density between invasive and non-invasive patients (SMD  = 1.81, 95%CI  = 0.39–3.23, P = 0.013). However, there were no significant difference in PTTG expression between functional and non-functional patients with pituitary adenomas (OR  = 1.11, 95%CI  = 0.58–2.10, P = 0.753). No publication bias was detected in this meta-analysis (all P>0.05). Conclusion: This present meta-analysis suggests that PTTG expression may be associated with tumor invasiveness and microvessel density of pituitary adenomas, while no correlations with functional status was found. [ABSTRACT FROM AUTHOR]

Published
2014
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