8 results on '"Diehl, David"'
Search Results
2. An Integrated Framework for Studying How Schools Respond to External Pressures.
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Diehl, David K. and Golann, Joanne W.
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INSTITUTIONAL environment ,EDUCATIONAL change ,LANDSCAPE changes ,ORGANIZATIONAL sociology ,SCHOOL environment ,MODEL theory - Abstract
The changing educational landscape requires new organizational frameworks to understand how schools and universities make sense of and respond to broader institutional forces like accountability, diversity, and the market. In this article, we draw on recent innovations in organizational theory to propose a model that identifies two general processes through which pressures from the environment shape educational practice in schools: filtering and local adaptation. We review three areas where researchers have studied filtering and local adaptation—routines, sensemaking, and networks—to illustrate how these processes are currently being applied in education and how this work can be extended. We also identify studies that have begun to integrate these different areas of scholarship and propose directions for future research. This article offers education researchers new to the field conceptual tools for guiding their analysis and assists more seasoned researchers in situating their studies in a broader context of institutional maintenance, change, and heterogeneity. [ABSTRACT FROM AUTHOR]
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- 2023
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3. Endoscopic ultrasound-directed transgastric ERCP (EDGE): a retrospective multicenter study.
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Runge, Thomas M., Chiang, Austin L., Kowalski, Thomas E., James, Theodore W., Baron, Todd H., Nieto, Jose, Diehl, David L., Krafft, Matthew R., Nasr, John Y., Kumar, Vikas, Khara, Harshit S., Irani, Shayan, Patel, Arpan, Law, Ryan J., Loren, David E., Schlachterman, Alex, Hsueh, William, Confer, Bradley D., Stevens, Tyler K., and Chahal, Prabhleen
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ENDOSCOPIC retrograde cholangiopancreatography ,GASTRIC bypass ,GASTRIC mucosa ,RESEARCH ,ENDOSCOPIC ultrasonography ,RESEARCH methodology ,RETROSPECTIVE studies ,MEDICAL cooperation ,EVALUATION research ,COMPARATIVE studies ,ENDOSCOPIC gastrointestinal surgery - Abstract
Background: Endoscopic ultrasound-directed transgastric endoscopic retrograde cholangiopancreatography (ERCP; EDGE) is an alternative to enteroscopy- and laparoscopy-assisted ERCP in patients with Roux-en-Y gastric bypass anatomy. Although short-term results are promising, the long-term outcomes are not known. The aims of this study were: (1) to determine the rates of long-term adverse events after EDGE, with a focus on rates of persistent gastrogastric or jejunogastric fistula; (2) to identify predictors of persistent fistula; (3) to assess the outcomes of endoscopic closure when persistent fistula is encountered.Methods: This was a multicenter retrospective study involving 13 centers between February 2015 and March 2019. Adverse events were defined according to the ASGE lexicon. Persistent fistula was defined as an upper gastrointestinal series or esophagogastroduodenoscopy showing evidence of fistula.Results: 178 patients (mean age 58 years, 79 % women) underwent EDGE. Technical success was achieved in 98 % of cases (175/178), with a mean procedure time of 92 minutes. Periprocedural adverse events occurred in 28 patients (15.7 %; mild 10.1 %, moderate 3.4 %, severe 2.2 %). The four severe adverse events were managed laparoscopically. Persistent fistula was diagnosed in 10 % of those sent for objective testing (9/90). Following identification of a fistula, 5 /9 patients underwent endoscopic closure procedures, which were successful in all cases.Conclusions: The EDGE procedure is associated with high clinical success rates and an acceptable risk profile. Persistent fistulas after lumen-apposing stent removal are uncommon, but objective testing is recommended to identify their presence. When persistent fistulas are identified, endoscopic treatment is warranted, and should be successful in closing the fistula. [ABSTRACT FROM AUTHOR]- Published
- 2021
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4. Practice patterns, techniques, and outcomes of flexible endoscopic myotomy for Zenker's diverticulum: a retrospective multicenter study.
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Mittal, Chetan, Diehl, David L., Draganov, Peter V., Jamil, Laith H., Khalid, Ammara, Khara, Harshit S., Khullar, Vikas, Law, Ryan, Lo, Simon K., Mathew, Abraham, Mirakhor, Ebrahim, Sedarat, Alireza, Sharma, Neil, Sharzehi, Setareh, Tavakkoli, Anna, Thaker, Adarsh, Thosani, Nirav, Yang, Dennis, Zelt, Christina, and Wagh, Mihir S.
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DIVERTICULUM , *RETROSPECTIVE studies , *ENDOSCOPY , *MYOTOMY , *ESOPHAGEAL diverticula , *ESOPHAGOSCOPY , *RESEARCH , *RESEARCH methodology , *DEGLUTITION disorders , *MEDICAL cooperation , *EVALUATION research , *TREATMENT effectiveness , *COMPARATIVE studies - Abstract
Background: Flexible endoscopic myotomy has been increasingly performed for Zenker's diverticulum using various endoscopic techniques and devices. The main aims of this study were to assess practice patterns and compare outcomes of endoscopic myotomy for Zenker's diverticulum.Methods: Procedures performed at 12 tertiary endoscopy centers from 1/2012 to 12/2018 were reviewed. Patients (≥ 18 years) with Zenker's diverticulum who had dysphagia and/or regurgitation and underwent endoscopic myotomy were included. Outcomes assessed included technical success, clinical success, and adverse events.Results: 161 patients were included. Traditional endoscopic septotomy was performed most frequently (137/161, 85.1 %) followed by submucosal dissection of the septum and myotomy (24/161, 14.9 %). The hook knife (43/161, 26.7 %) and needle-knife (33/161, 20.5 %) were used most frequently. Overall, technical and clinical success rates were 98.1 % (158/161) and 78.1 % (96/123), respectively. Adverse events were noted in 13 patients (8.1 %). There was no significant difference in technical and clinical success between traditional septotomy and submucosal dissection groups (97.1 % vs. 95.8 %, P = 0.56 and 75.2 % vs. 90.9 %, P = 0.16, respectively). Clinical success was higher with the hook knife (96.7 %) compared with the needle-knife (76.6 %) and insulated tip knife (47.1 %). Outcomes were similar between centers performing > 20, 11 - 20, and ≤ 10 procedures.Conclusions: Flexible endoscopic myotomy is an effective therapy for Zenker's diverticulum, with a low rate of adverse events. There was no significant difference in outcomes between traditional septotomy and a submucosal dissection approach, or with centers with higher volume, though clinical success was higher with the hook knife. [ABSTRACT FROM AUTHOR]- Published
- 2021
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5. A multicenter experience of through-the-scope balloon-assisted enteroscopy in surgically altered gastrointestinal anatomy.
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Cai, Jennifer, Diehl, David, Kiesslich, Ralf, Storm, Andrew, El Zein, Mohamad, Tieu, Alan, Hoffman, Arthur, Singh, Vikesh, Khashab, Mouen, Okolo, Patrick, Kumbhari, Vivek, Cai, Jennifer X, Diehl, David L, Storm, Andrew C, El Zein, Mohamad H, Tieu, Alan H, Singh, Vikesh K, Khashab, Mouen A, and Okolo, Patrick I 3rd
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ENTEROSCOPY , *SURGICAL & topographical anatomy , *INTESTINE examination , *SURGICAL stents , *BILIARY tract , *SMALL intestine surgery , *COMPARATIVE studies , *ENDOSCOPES , *ENDOSCOPIC retrograde cholangiopancreatography , *SMALL intestine , *RESEARCH methodology , *MEDICAL cooperation , *RESEARCH , *SURGICAL complications , *EVALUATION research , *RETROSPECTIVE studies ,TREATMENT of surgical complications - Abstract
Background: Surgically altered gastrointestinal anatomy poses challenges for deep enteroscopy. Current overtube-assisted methods have long procedure times and utilize endoscopes with smaller working channels that preclude use of standard accessories. A through-the-scope balloon-assisted enteroscopy (TTS-BAE) device uses standard endoscopes with a large working channel to allow metallic and plastic stent insertion. We aim to determine the efficacy and safety of TTS-BAE in patients with altered surgical anatomy.Methods: A retrospective, multicenter study of TTS-BAE in altered anatomy patients at two USA and one German institution was performed between January 2013 and December 2014. Type of anatomy, procedure indication and duration, adverse events, and target, technical, and clinical success were recorded.Results: A total of 32 patients (mean age 54 years, Caucasian 81.6%, female 42.1%, mean BMI 25.4 kg/m2) underwent 38 TTS-BAE procedures. Thirty-two percent of cases had a prior attempt at conventional enteroscopy which failed to reach the target site. The target was successfully reached in 23 (60.5%) cases. Of the 23 cases that reached the intended target, 22 (95.7%) achieved technical success and 21 (91.3%) achieved clinical success. The median procedure time was 43 min. Target, technical, and clinical success rates for TTS-BAE-assisted ERCP (n = 31) were 58.1, 54.8 and 54.8%. Seven self-expandable metallic stents (five biliary, two jejunal) were attempted, and all successfully deployed. Adverse events occurred in 4 (10.4%) cases, including one luminal perforation.Conclusion: TTS-BAE is an alternative to overtube-assisted enteroscopy that is comparable in safety in patients with surgically altered anatomies. Technical success in the instances where the target had been reached was excellent. TTS-BAE confers an advantage over overtube-assisted enteroscopy as it can facilitate the deployment of self-expandable metallic stents in the biliary tree and deep small bowel. [ABSTRACT FROM AUTHOR]- Published
- 2017
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6. Foster care for teenagers: Motivators, barriers, and strategies to overcome barriers.
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Baer, Lauren and Diehl, David K.
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CHILD rearing , *FOSTER home care , *FOSTER parents , *GROUNDED theory , *HEALTH services accessibility , *INTERVIEWING , *RESEARCH methodology , *MOTIVATION (Psychology) , *SATISFACTION , *STEREOTYPES , *QUALITATIVE research , *FINANCIAL management , *PSYCHOSOCIAL factors , *ADOLESCENCE - Abstract
There has long been a shortage of homes for teenagers in foster care due in part to the reality that many people who foster choose not to foster teenagers. An understanding of factors that influence people's willingness to foster teenagers might support an increased supply of available homes for teenagers. Through this qualitative study, we explored why some foster parents are motivated to foster teenagers, what barriers prevent other foster parents from fostering teenagers, and whether there are effective strategies for foster parents to overcome barriers to fostering teenagers. The first author collected data through 19 semi-structured interviews with 16 foster parents and 6 foster care agency staff in Tennessee and used the constant-comparative method to analyze the data and allow grounded theory to emerge. Through this study, we found that people were motivated to foster teenagers by a combination of overarching motivators and teen-specific motivators. Overarching motivators, which influence people who do foster teenagers as well as those who do not, included making a difference and having a family. Financial compensation emerged as an overarching facilitator of fostering. Teen-specific motivators were both foster parent-oriented – ability, lifestyle, passion, preference, and satisfaction – and teenager-oriented – compassion and teenagers' progress. Key barriers to fostering teenagers were also foster parent-oriented – desire to raise children from a young age and preference – as well as teenager-oriented – bad experience, fear, and stereotyping. Strategies for foster parents to overcome barriers to fostering teenagers that emerged through this study were firsthand experience with teenagers in foster care, especially through respite care, and secondhand learning about things like trauma and youth's needs, and agencies are able to facilitate both types of strategies. These findings have implications for research, policy, and practice. • General motivations to foster do not alone explain the choice to foster teenagers. • People's willingness to foster teenagers is affected by teen-specific motivators. • There are specific barriers that deter people from fostering teenagers. • Certain strategies can help foster parents overcome barriers to fostering teenagers. [ABSTRACT FROM AUTHOR]
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- 2019
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7. A US Multicenter Study of Safety and Efficacy of Fully Covered Self-Expandable Metallic Stents in Benign Extrahepatic Biliary Strictures.
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Saxena, Payal, Diehl, David, Kumbhari, Vivek, Shieh, Frederick, Buscaglia, Jonathan, Sze, Wilson, Kapoor, Sumit, Komanduri, Srinadh, Nasr, John, Shin, Eun, Singh, Vikesh, Lennon, Anne, Kalloo, Anthony, Khashab, Mouen, Diehl, David L, Buscaglia, Jonathan M, Shin, Eun Ji, Lennon, Anne Marie, Kalloo, Anthony N, and Khashab, Mouen A
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BILE ducts , *COMPARATIVE studies , *CHOLESTASIS , *ENDOSCOPIC retrograde cholangiopancreatography , *RESEARCH methodology , *MEDICAL cooperation , *METALS , *PROSTHETICS , *COMPLICATIONS of prosthesis , *RESEARCH , *SURGICAL stents , *TIME , *DISEASE relapse , *EVALUATION research , *SPECIALTY hospitals , *TREATMENT effectiveness , *RETROSPECTIVE studies , *FOREIGN body migration , *MEDICAL device removal , *CHOLANGITIS , *MEDICAL drainage , *EQUIPMENT & supplies , *DIAGNOSIS , *THERAPEUTICS - Abstract
Background: Endoscopic therapy is considered first line for management of benign biliary strictures (BBSs). Placement of plastic stents has been effective but limited by their short-term patency and need for repeated procedures. Fully covered self-expandable metallic stents (FCSEMSs) offer longer-lasting biliary drainage without the need for frequent exchanges.Aims: The aim of this study was to assess the efficacy and safety of FCSEMS in patients with BBS.Methods: A retrospective review of all patients who underwent ERCP and FCSEMS placement at five tertiary referral US hospitals was performed. Stricture resolution and adverse events related to ERCP and/or stenting were recorded.Results: A total of 123 patients underwent FCSEMS placement for BBS and 112 underwent a subsequent follow-up ERCP. The mean age was 62 years (±15.6), and 57% were males. Stricture resolution occurred in 81% of patients after a mean of 1.2 stenting procedures (mean stent dwell time 24.4 ± 2.3 weeks), with a mean follow-up of 18.5 months. Stricture recurrence occurred in 5 patients, and 3 patients required surgery for treatment of refractory strictures. Stent migration (9.7%) was the most common complication, followed by stent occlusion (4.9%), cholangitis (4.1%), and pancreatitis (3.3%). There was one case of stent fracture during removal, and one stent could not be removed. There was one death due to cholangitis.Conclusions: Majority of BBS can be successfully managed with 1-2 consecutive FCSEMS with stent dwell time of 6 months. [ABSTRACT FROM AUTHOR]- Published
- 2015
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8. Reevaluation and Identification of the Best Immunohistochemical Panel (pVHL, Maspin, S100P, IMP-3) for Ductal Adenocarcinoma of the Pancreas.
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Haiyan Liu, Jianhui Shi, Anandan, Vasuki, Wang, Hanlin L., Diehl, David, Blansfield, Joseph, Gerhard, Glenn, and Fan Lin
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DUCTAL carcinoma , *BIOPHYSICS , *IMMUNOHISTOCHEMISTRY , *RESEARCH methodology , *NEEDLE biopsy , *PANCREATIC tumors , *RESEARCH funding , *STAINS & staining (Microscopy) , *TUMOR markers , *TISSUE arrays , *DESCRIPTIVE statistics , *DIAGNOSIS - Abstract
Context.-Differentiation of ductal adenocarcinoma of the pancreas from non-neoplastic pancreatic tissues can be challenging, especially in small biopsy and fine-needle aspiration specimens. Objective.-To investigate the utility of 26 immunohistochemical markers (CAM 5.2, CK [cytokeratin] 7, CK20, CK17, CK19, MUC1, MUC2, MUC4, MUC5AC, MUC6, p53, DPC4/SMAD4, CDX2, pVHL [von Hippel-Lindau tumor suppressor gene protein], S100P, IMP-3 [insulin-like growth factor 2 messenger RNA binding protein 3], maspin, mesothelin, claudin 4, claudin 18, annexin A8, fascin, PSCA [prostate stem cell antigen], MOC31, CEA [carcinoembryonic antigen], and CA19-9 [cancer antigen 19-9]) in the diagnosis of ductal adenocarcinoma of the pancreas. Design.-Immunohistochemical staining for these markers was performed in 60 cases of pancreatic ductal adenocarcinoma on routine and tissue microarray sections. In addition, immunohistochemical staining for maspin, S100P, IMP-3, and pVHL was performed on cell blocks from 67 pancreatic fine-needle aspiration cases, including 44 cases of pancreatic ductal adenocarcinoma. Results.-The results demonstrated that (1) more than 90% of cases of ductal adenocarcinoma were positive for maspin, S100P, and IMP-3; (2) nearly all adenocarcinoma cases were negative for pVHL, whereas nonneoplastic ducts and acini were positive for pVHL in all cases; (3) normal/reactive pancreatic ducts were frequently positive for CK7, CK19, MUC1, MUC6, CA19-9,MOC31, PSCA, mesothelin, annexin A8, claudin 4, and claudin 18; (4) normal pancreatic ducts were usually negative for IMP-3, maspin, S100P, CK17, MUC2, MUC4, and MUC5AC; (5) 60% of adenocarcinomas were negative for DPC4/SMAD4; and (6) strong background staining was frequently seen with fascin, PSCA, and annexin A8. Conclusions.-pVHL, maspin, S100P, and IMP-3 constitute the best diagnostic panel of immunomarkers for confirming the diagnosis of pancreatic ductal adenocarcinoma in both surgical and fine-needle aspiration specimens [ABSTRACT FROM AUTHOR]
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- 2012
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