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Open science and preprints have invited a larger audience of readers, especially during the pandemic. Consequently, communicating the limitations and uncertainties of research to a broader public has become important over the entire information lifecycle. This paper brings together reports from the NISO Plus 2021 conference session "Misinformation and truth: from fake news to retractions to preprints". We discuss the validation and verification of scientific information at the preprint stage in order to support sound and open science standards, at the publication stage in order to limit the spread of retracted research, and after publication, to fight fake news about health-related research by mining open access content. [ABSTRACT FROM AUTHOR]