1. Examination of micro-superficial lesions of up to 5 mm in size in the pharyngolaryngeal region.
- Author
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Ueda, T, Yumii, K, Urabe, Y, Chikuie, N, Takumida, M, Taruya, T, Kono, T, Hamamoto, T, Hattori, M, Oka, S, Tanaka, S, Ishino, T, and Takeno, S
- Subjects
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DISEASE progression , *PREDICTIVE tests , *ACADEMIC medical centers , *ACQUISITION of data , *RETROSPECTIVE studies , *CANCER patients , *MEDICAL records , *RESEARCH funding , *SENSITIVITY & specificity (Statistics) , *THORACOSCOPY , *SQUAMOUS cell carcinoma , *SYMPTOMS ,LARYNGEAL tumors ,PHARYNX tumors - Abstract
Objective: For low-grade intraepithelial neoplasia cases, pharyngolaryngeal lesions equal to or less than 5 mm in size do not generally progress to invasive carcinoma. However, micro-superficial lesions equal to or less than 5 mm that showed rapid growth have been recently encountered. This study aimed to identify the characteristics of preferential progression of lesions equal to or less than 5 mm in size. Method: Gross findings, endoscopic findings and pathological results of 55 lesions measuring equal to or less than 5 mm in diameter were retrospectively reviewed to identify factors that distinguish squamous cell carcinoma or high-grade intraepithelial neoplasia from low-grade intraepithelial neoplasia or non-atypia lesions. Results: The overall sensitivity, specificity, accuracy, and positive and negative predictive value of background colouration and intrapapillary capillary loop pattern in differentiation of squamous cell carcinoma or high-grade intraepithelial neoplasia from low-grade intraepithelial neoplasia or non-atypia lesions were all 100 per cent. Conclusion: Diagnosis based on background colouration and the intrapapillary capillary loop pattern on narrow-band imaging facilitates the pathological examination of lesions measuring equal to or less than 5 mm. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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