1. Primary rhabdomyosarcoma of the distal femoral diaphysis: a case report and review of the literature.
- Author
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Bressner JA, McCarthy EF, Fayad LM, and Morris CD
- Subjects
- Adult, Diagnosis, Differential, Diaphyses diagnostic imaging, Diaphyses pathology, Humans, Male, Rhabdomyosarcoma diagnosis, Sarcoma, Ewing diagnosis, Sarcoma, Ewing pathology, Femoral Neoplasms diagnostic imaging, Femoral Neoplasms pathology, Rare Diseases diagnostic imaging, Rare Diseases pathology, Rhabdomyosarcoma diagnostic imaging, Rhabdomyosarcoma pathology
- Abstract
Primary rhabdomyosarcoma of the bone is an extremely rare condition with few examples reported in the literature. We present the case of a 34-year-old male who presented with a lesion in the distal femur with initial imaging features consistent with Ewing sarcoma. Histologically, the lesion consisted of atypical pleomorphic polygonal rhabdomyoblasts demonstrating focal desmin and myogenin expression. A diagnosis of pleomorphic rhabdomyosarcoma was rendered. Despite systemic treatment and surgery, this patient experienced a rapidly progressive disease course. We believe this is only the second report in the orthopedic literature of a case of primary pleomorphic rhabdomyosarcoma of the bone. The key imaging, pathologic, and clinical findings are discussed.
- Published
- 2016
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