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A rhodamine spirolactam derivative ( 1 ) is developed as a colormetric and fluorescent probe for trivalent aluminum ions (Al 3+ ). It exhibits a highly sensitive “turn-on” fluorescent response toward Al 3+ with a 70-fold fluorescence intensity enhancement under 2 equiv. of Al 3+ added. The probe can be applied to the quantification of Al 3+ with a linear range covering from 5.0 × 10 −7 to 2.0 × 10 −5 M and a detection limit of 4.0 × 10 −8 M. Most importantly, the fluorescence changes of the probe are remarkably specific for Al 3+ in the presence of other metal ions, which meet the selective requirements for practical application. Moreover, the experiment results show that the response behavior of 1 towards Al 3+ is pH independent in neutral condition (pH 6.0–8.0) and the response of the probe is fast (response time less than 3 min). In addition, the proposed probe has been used to detect Al 3+ in water samples and image Al 3+ in living cells with satisfying results. [ABSTRACT FROM AUTHOR]

Abstract: A new rhodamine-based compound (1) has been synthesized and applied as an “off–on” chemosensor for Fe3+. The comparison of this method with some other fluorescence methods for Fe3+ indicates that the method can detect Fe3+ in living cells by fluorescence enhancement and color changes with high sensitivity and selectivity. The fluorescence intensity of 1 is significantly increased about 60-fold with 20 equiv of Fe3+ added. Most importantly, the fluorescence changes of the chemosensor are remarkably specific for Fe3+ in the presence of other metal ions, which meet the selective requirements for practical application. Moreover, the experiment results show that the response behavior of 1 towards Fe3+ is pH independent in neutral condition (pH 6.0–8.0) and the response of the chemosensor is fast (response time less than 2 min). In addition, the proposed chemosensor has been used for imaging of Fe3+ in living cells with satisfying results. [Copyright &y& Elsevier]